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Percutaneous Injection of Thrombin for the Treatment of Pseudoaneurysms After Catheterization

An Alternative to Sonographically Guided Compression

John A. Pezzullo1, Damian E. Dupuy and John J. Cronan

1 All authors: Department of Diagnostic Imaging, Brown University School of Medicine and Rhode Island Hospital, 593 Eddy St., Providence, RI 02903.



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Fig. 1. —54-year-old woman with pseudoaneurysm of common femoral artery after routine cardiac catheterization. Gray-scale sonogram reveals 22-gauge spinal needle (arrow) in center of pseudoaneurysm lumen with instantaneous echogenic thrombus formation above beveled edge.

 


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Fig. 2A. —67-year-old man with pseudoaneurysm after percutaneous transluminal coronary angioplasty. Color flow sonogram reveals characteristic to-and-fro blood-flow pattern.

 


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Fig. 2B. —67-year-old man with pseudoaneurysm after percutaneous transluminal coronary angioplasty. Color sonogram obtained after injection of 1000 U of thrombin reveals rapid thrombosis of pseudoaneurysm lumen (arrow) with residual flow at periphery (arrowhead).

 


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Fig. 2C. —67-year-old man with pseudoaneurysm after percutaneous transluminal coronary angioplasty. Repeated color flow image obtained after injection of additional 1000 U of thrombin reveals complete thrombosis.

 

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