AJR
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Abstract Freely available
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Pirovano, G.
Right arrow Articles by Spinazzi, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Pirovano, G.
Right arrow Articles by Spinazzi, A.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?

Evaluation of the Accuracy of Gadobenate Dimeglumine-Enhanced MR Imaging in the Detection and Characterization of Focal Liver Lesions

Gianpaolo Pirovano1, Angelo Vanzulli2, Luis Marti-Bonmati3, Luigi Grazioli4, Riccardo Manfredi5, Alina Greco6, Nicolaus Holzknecht7, Heike E. Daldrup-Link8, Ernst Rummeny8, Bernd Hamm9, Valerie Arneson1, Luigi Imperatori1, Miles A. Kirchin1 and Alberto Spinazzi1

1 Bracco, Medical and Regulatory Affairs, Via Egidio Folli 50, 20134 Milan, Italy.
2 Department of Radiology, Scientific Institute S. Raffaele, University Hospital, Via Olgettina 60, 20132 Milan, Italy.
3 Department of Radiology, Hospital Universitario Dr. Peset, Valencia, Spain.
4 Il Servizio di Radiologia, Ente Ospedaliero «Spedali Civili», Piazzale Ospedale 1, 25100 Brescia, Italy.
5 Instituto di Radiologia, Policlinico «A. Gemelli», Largo A. Gemelli 8, 00168 Roma, Italy.
6 MR Imaging Centre, Princess Grace Hospital, Ave. Pasteur, 98000 Monaco, Principaute de Monaco.
7 Ludwig-Maximilians-Universität-München, Institut für Radiologische Klinik, Klinikum Marchioninistr. 15, 81377 München, Germany.
8 Westfälische Wilhelms-Universität Münster, Institut für Klinische Radiologie, Röntgendiagnostik, A.-Schweitzer-Str. 33, 48129 Münster, Germany.
9 Institut für Röntgendiagnostik, Medizinische Fakultät der Humboldt-Universität, Charité, Schumannstr. 20/21, 10098 Berlin, Germany.



View larger version (138K):

[in a new window]
  		Fig. 1A. —68-year-old man with hepatic metastasis from pancreatic carcinoma. Axial unenhanced breath-hold T1-weighted two-dimensional (2D) fast low-angle shot (FLASH) image shows small hypointense lesion (arrow) in segment VI of liver.

 


View larger version (102K):

[in a new window]
  		Fig. 1B. —68-year-old man with hepatic metastasis from pancreatic carcinoma. Axial unenhanced T2-weighted turbo spin-echo image reveals lesion as mildly hyperintense mass (arrowhead).

 


View larger version (110K):

[in a new window]
  		Fig. 1C. —68-year-old man with hepatic metastasis from pancreatic carcinoma. On dynamic scanning, breath-hold T1-weighted 2D FLASH images obtained at 30 (C) and 90 sec (D) after contrast injection show lesion as markedly hypointense. Hyperintense thin rim (small arrow, C) has faded by 90-sec acquisition (D). Note large mass in tail of pancreas (large arrow, C).

 


View larger version (119K):

[in a new window]
  		Fig. 1D. —68-year-old man with hepatic metastasis from pancreatic carcinoma. On dynamic scanning, breath-hold T1-weighted 2D FLASH images obtained at 30 (C) and 90 sec (D) after contrast injection show lesion as markedly hypointense. Hyperintense thin rim (small arrow, C) has faded by 90-sec acquisition (D). Note large mass in tail of pancreas (large arrow, C).

 


View larger version (128K):

[in a new window]
  		Fig. 1E. —68-year-old man with hepatic metastasis from pancreatic carcinoma. Axial contrast-enhanced breath-hold T1-weighted 2D FLASH image obtained 90 min after initiation of contrast administration reveals good delineation of lesion against strongly enhanced normal liver parenchyma. Note target appearance of lesion with hyperintense center, which is typical of metastasis.

 


View larger version (125K):

[in a new window]
  		Fig. 2A. —66-year-old woman with hepatocellular carcinoma in cirrhotic liver. Axial unenhanced breath-hold T1-weighted two-dimensional (2D) fast low-angle shot (FLASH) image reveals 2.5-cm slightly hyperintense mass in segment VI of liver (large arrow). Note thin hypointense rim corresponding to histologically proven pseudocapsule and tiny hyperintense satellite lesion (small arrow).

 


View larger version (119K):

[in a new window]
  		Fig. 2B. —66-year-old woman with hepatocellular carcinoma in cirrhotic liver. Axial unenhanced T2-weighted spin-echo image fails to reveal lesions.

 


View larger version (121K):

[in a new window]
  		Fig. 2C. —66-year-old woman with hepatocellular carcinoma in cirrhotic liver. On dynamic scanning, breath-hold T1-weighted 2D FLASH images obtained at 25 sec (C) and 90 sec (D) after contrast injection show larger lesion as homogeneously hyperintense in C (arrow) but as hypointense to liver in D (arrow).

 


View larger version (127K):

[in a new window]
  		Fig. 2D. —66-year-old woman with hepatocellular carcinoma in cirrhotic liver. On dynamic scanning, breath-hold T1-weighted 2D FLASH images obtained at 25 sec (C) and 90 sec (D) after contrast injection show larger lesion as homogeneously hyperintense in C (arrow) but as hypointense to liver in D (arrow).

 


View larger version (124K):

[in a new window]
  		Fig. 2E. —66-year-old woman with hepatocellular carcinoma in cirrhotic liver. Axial contrast-enhanced T1-weighted breath-hold 2D FLASH image obtained 90 min after initiation of contrast administration reveals lesion as isointense to enhanced normal liver parenchyma. Histologic analysis revealed extensive intralesional fatty metaplasia.

 


View larger version (118K):

[in a new window]
  		Fig. 3A. —55-year-old man with cavernous hemangioma. Axial unenhanced T1-weighted spin-echo image shows large hypointense lesion in lateral part of left lobe of liver (arrow).

 


View larger version (134K):

[in a new window]
  		Fig. 3B. —55-year-old man with cavernous hemangioma. Axial unenhanced T2-weighted spin-echo image reveals markedly homogeneous, hyperintense lesion.

 


View larger version (129K):

[in a new window]
  		Fig. 3C. —55-year-old man with cavernous hemangioma. On dynamic scanning, breath-hold two-dimensional fast field echo images obtained at 30 sec (C) and 7 min (D) after contrast injection reveal intense peripheral nodular enhancement of lesion. By 7 min after injection almost complete filling-in has occurred. Note only central portion of lesion remains hypointense (arrow, D). Enhancement pattern is typical for cavernous hemangioma.

 


View larger version (130K):

[in a new window]
  		Fig. 3D. —55-year-old man with cavernous hemangioma. On dynamic scanning, breath-hold two-dimensional fast field echo images obtained at 30 sec (C) and 7 min (D) after contrast injection reveal intense peripheral nodular enhancement of lesion. By 7 min after injection almost complete filling-in has occurred. Note only central portion of lesion remains hypointense (arrow, D). Enhancement pattern is typical for cavernous hemangioma.

 


View larger version (129K):

[in a new window]
  		Fig. 3E. —55-year-old man with cavernous hemangioma. Axial contrast-enhanced T1-weighted spin-echo image obtained 60 min after initiation of contrast administration reveals lesion as isointense or slightly hyperintense with hypointense central portion against enhanced normal liver parenchyma (arrow).

 

Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?



HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2000 by the American Roentgen Ray Society.