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T2 Relaxation Rate as an Index of Pituitary Iron Overload in Patients with ß-Thalassemia Major

Maria I. Argyropoulou1, Zafiroula Metafratzi1, Dimitrios N. Kiortsis2, Spiros Bitsis3, Agathocles Tsatsoulis3 and Stavros Efremidis1

1 Department of Radiology, School of Medicine, University of Ioannina, 45110, Ioannina, Greece.
2 Department of Physiology, School of Medicine, University of Ioannina, 45110, Ioannina, Greece.
3 Department of Internal Medicine, Endocrine Unit, School of Medicine, University of Ioannina, 45110, Ioannina, Greece.



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  		Fig. 1. —Graph shows T2 relaxation rate (1/T2) (msec-1) versus serum ferritin concentration (ng/mL) in 29 patients with ß-thalassemia major. Linear fit function (1/T2 = ax + b) was obtained from least square fit of 29 data points, where x is serum ferritin concentration; a and b could be determined by a = 1.543 x 10-2 x ng/mL x msec-1 (slope) and b = 2.151 x 10-6 x msec-1 (intercept).

 

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