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Radiofrequency Ablation of 100 Hepatic Metastases with a Mean Follow-Up of More Than 1 Year

Thierry de Baere1, Dominique Elias2, Clarisse Dromain1, Mostafa Gamal El Din1, Viseth Kuoch1, Michel Ducreux3, Valerie Boige3, Nathalie Lassau1, Veronique Marteau1, Philippe Lasser2 and Alain Roche1

1 Departement d'Imagerie Medicale, Institut Gustave Roussy, Villejuif, France.
2 Departement de Chirurgie, Institut Gustave Roussy, 94805 Villejuif Cedex, France.
3 Departement de Medecine, Institut Gustave Roussy, 94805 Villejuif Cedex, France.



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Fig. 1A. 68-year-old women with colon cancer. Sonogram obtained after current had been delivered for few seconds shows hypoechoic metastatic tumor nodule (arrowheads) with radiofrequency electrode needle inserted through it. Hyperechoic zone (arrow) can be seen at tip of electrode needle.

 


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Fig. 1B. 68-year-old woman with colon cancer. Sonogram obtained at end of procedure, 18 min after A, shows that hyperechoic zone has enlarged; it now encompasses location of metastasis.

 


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Fig. 2A. 54-year-old man with colon cancer. CT scan obtained 3 months after right hepatectomy (note staples at edge of segment IV) shows hepatic 3-cm-diameter metastasis in segment II (arrow).

 


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Fig. 2B. 54-year-old man with colon cancer. CT scan obtained at same level as A 2 months after radiofrequency ablation of tumor. Hypodense "scar" without contrast enhancement is completely covering site of metastasis, with mild dilatation of biliary tract upstream.

 


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Fig. 3A. 57-year-old woman with colon cancer metastasis who had been treated with radiofrequency ablation 3 months earlier. Arterial phase CT scan obtained at site of radiofrequency ablation shows hypodense nodule (arrow) without contrast enhancement.

 


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Fig. 3B. 57-year-old woman with colon cancer metastasis who had been treated with radiofrequency ablation 3 months earlier. T1-weighted MR image obtained same day as A shows nodule that is hyperintense because of hemorrhage.

 


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Fig. 3C. 57-year-old woman with colon cancer metastasis who had been treated with radiofrequency ablation 3 months earlier. Dynamic MR image shows gadolinium uptake at posterior margin of nodule later confirmed to be tumor regrowth (arrow).

 


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Fig. 4A. 49-year-old woman with colon cancer. CT scan obtained 24 hr after radiofrequency ablation of subcapsular metastasis from colon cancer. Hypodense area without contrast enhancement corresponds to treated region.

 


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Fig. 4B. 49-year-old woman with colon cancer. CT scan obtained 2 months after A revealed air—fluid level corresponding to abscess that was drained percutaneously.

 

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