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Contrast-Enhanced Carotid MR Angiography with Commercially Available Triggering Mechanisms and Elliptic Centric Phase Encoding

J. Kevin De Marco1, Steven Schonfeld1, Irwin Keller1 and Matt A. Bernstein2

1 Laurie Imaging Center, University Radiology Group, University of Medicine and Dentistry New Jersey, 141 French St., New Brunswick, NJ 08901.
2 Department of Diagnostic Radiology, Mayo Clinic and Foundation, 200 First St. S.W., Rochester, MN 55905.



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Fig. 1A. 78-year-old woman with severe carotid stenosis as depicted equally well with multiple overlapping thin-section acquisition MR angiography, contrast-enhanced MR angiography, and intraarterial digital subtraction angiography. Maximum-intensity-projection image from multiple overlapping thin-section acquisition MR angiogram shows focal severe stenosis involving left carotid bulb (straight arrow). Turbulent flow disrupts flow-related enhancement in internal carotid artery just beyond stenosis (curved arrow).

 


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Fig. 1B. 78-year-old woman with severe carotid stenosis as depicted equally well with multiple overlapping thin-section acquisition MR angiography, contrast-enhanced MR angiography, and intraarterial digital subtraction angiography. Maximum-intensity-projection image from contrast-enhanced MR angiogram reveals similar focal severe stenosis (straight arrow), but with better delineation of internal carotid artery just beyond stenosis (curved arrow).

 


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Fig. 1C. 78-year-old woman with severe carotid stenosis as depicted equally well with multiple overlapping thin-section acquisition MR angiography, contrast-enhanced MR angiography, and intraarterial digital subtraction angiography. Intraarterial digital subtraction angiogram confirms focal severe stenosis caused by densely calcified plaque in carotid bulb (straight arrow) with bulbous dilatation of internal carotid artery just beyond stenosis (curved arrow). Both observers believed vessel margins were sharper on maximum-intensity-projection images from multiple overlapping thin-section acquisition MR angiogram (A), but contrast-enhanced MR angiograms (B) looked more like those on intraarterial digital subtraction angiography (C). Diagnostic confidence of surgical lesion was high for both MR angiographic techniques.

 


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Fig. 2A. 67-year-old woman with ulceration better depicted with contrast-enhanced MR angiography. Maximum-intensity-projection image from multiple overlapping thin-section acquisition MR angiogram reveals severe stenosis. Note faintest suggestion of ulceration (arrow).

 


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Fig. 2B. 67-year-old woman with ulceration better depicted with contrast-enhanced MR angiography. Maximum-intensity-projection image from contrast-enhanced MR angiogram shows focal outpouching compatible with ulceration (arrow). This ulceration was confirmed at surgery.

 


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Fig. 3A. 68-year-old man in whom length of severe carotid stenosis was overestimated with multiple overlapping thin-section acquisition MR angiography and not with contrast-enhanced MR angiography. Maximum-intensity-projection image from multiple overlapping thin-section acquisition MR angiogram suggests severe stenosis of long segment of proximal internal carotid artery.

 


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Fig. 3B. 68-year-old man in whom length of severe carotid stenosis was overestimated with multiple overlapping thin-section acquisition MR angiography and not with contrast-enhanced MR angiography. Maximum-intensity-projection image from contrast-enhanced MR angiogram details focal severe stenosis confirmed at surgery.

 


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Fig. 4A. 62-year-old woman in whom contrast-enhanced MR angiography overestimated stenosis compared with multiple overlapping thin-section acquisition MR angiography. Maximum-intensity-projection image from multiple overlapping thin-section acquisition MR angiogram reveals high-grade stenosis (arrow).

 


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Fig. 4B. 62-year-old woman in whom contrast-enhanced MR angiography overestimated stenosis compared with multiple overlapping thin-section acquisition MR angiography. Maximum-intensity-projection image from contrast-enhanced MR angiogram suggests critical stenosis (arrow). Sagittally reformatted maximum-intensity-projection image was not as sharp in this patient, perhaps related to less than optimal gadolinium contrast enhancement on these magnified images.

 


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Fig. 5A. 77-year-old woman with focal stenosis involving takeoff of great vessels as seen on contrast-enhanced MR angiography. Maximum-intensity-projection image from contrast-enhanced MR angiogram reveals tandem severe stenosis of left subclavian artery origin and farther distally at origin of left vertebral artery (arrows). Mild stenosis of origin of left common carotid artery is also seen. Note high-grade stenosis of left internal carotid artery at bifurcation and moderate stenosis involving right carotid bifurcation.

 


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Fig. 5B. 77-year-old woman with focal stenosis involving takeoff of great vessels as seen on contrast-enhanced MR angiography. Intraarterial digital subtraction angiogram of aortic arch and takeoff of great vessels confirms contrast-enhanced MR angiographic finding (arrows).

 

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