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Imaging Findings in Pseudocystic Osteosarcoma

Murali Sundaram1, William G. Totty2, Michael Kyriakos3, Douglas J. McDonald4 and Kurt Merkel5

1 Department of Radiology, St. Louis University Health Sciences Center, 3635 Vista at Grand, St. Louis, MO 63110-0250.
2 Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 S. Kingshighway, St. Louis, MO 63110.
3 Department of Surgical Pathology, Washington University School of Medicine, St. Louis, MO 63110.
4 Department of Orthopedic Surgery, Washington University School of Medicine, St. Louis, MO 63110.
5 Department of Orthopedic Surgery, St. Louis University Health Sciences Center, St. Louis, MO 63110-0250.



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Fig. 1A. Proximal tibial lesion in 7-year-old girl. Lateral radiograph of proximal leg shows expansive osteolytic lesion of proximal metaphysis. Note scalloping of anterior endosteal cortex.

 


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Fig. 1B. Proximal tibial lesion in 7-year-old girl. Lateral radiograph obtained 3 months after injection of steroids shows no change in metaphyseal lesion.

 


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Fig. 1C. Proximal tibial lesion in 7-year-old girl. Lateral radiograph obtained 33 months after A and 36 months after B shows interval growth of lesion. Note transverse fracture through middle of lesion. Minimal callus bridges fracture line anteriorly, indicating that fracture is subacute.

 


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Fig. 1D. Proximal tibial lesion in 7-year-old girl. Contrast-enhanced axial CT scan corresponding to C shows marked enhancement through medial portion of lesion.

 


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Fig. 2A. Tibial lesion in 3-year-old girl. Anteroposterior (A) and lateral (B) radiographs of right leg, June1998, show well-defined diametaphyseal osteolytic lesion of tibia with slight endosteal thinning. Lesion is well marginated, and on lateral image, fracture is identified in anterior cortex.

 


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Fig. 2B. Tibial lesion in 3-year-old girl. Anteroposterior (A) and lateral (B) radiographs of right leg, June1998, show well-defined diametaphyseal osteolytic lesion of tibia with slight endosteal thinning. Lesion is well marginated, and on lateral image, fracture is identified in anterior cortex.

 


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Fig. 2C. Tibial lesion in 30-year-old girl. Coronal (C) (TR/TE, 4500/96) and axial (D) (3500/119) MR images, 6 months after A and B, confirm intracompartmental confines of tumor with aneurysmal configuration.

 


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Fig. 2D. Tibial lesion in 3-year-old girl. Coronal (C) (TR/TE, 4500/96) and axial (D) (3500/119) MR images, 6 months after A and B, confirm intracompartmental confines of tumor with aneurysmal configuration.

 


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Fig. 3A. 34-year-old woman with eccentric osteolytic lesion in left femoral head and neck. Anteroposterior radiograph of left hip shows intracompartmental osteolytic lesion eccentrically located in femoral head and proximal neck and extending to intertrochanteric line.

 


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Fig. 3B. 34-year-old woman with eccentric osteolytic lesion in left femoral head and neck. Frog lateral image confirms eccentric intracompartmental lesion.

 


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Fig. 3C. 34-year-old woman with eccentric osteolytic lesion in left femoral head and neck. Axial CT scan of left hip joint reveals thin shell of bone containing lesion superolaterally without soft-tissue mass or intraosseous matrix.

 


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Fig. 3D. 34-year-old woman with eccentric osteolytic lesion in left femoral head and neck. T2-weighted MR axial image (TR/TE, 1950/90) shows no extraosseous mass.

 


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Fig. 4A. 26-year-old woman with lesion in tarsal navicular bone. Coned-down anteroposterior (A) and oblique (B) radiographs of mid foot show multilocular osteolytic lesion expanding tarsal navicular bone medially with intact cortex.

 


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Fig. 4B. 26-year-old woman with lesion in tarsal navicular bone. Coned-down anteroposterior (A) and oblique (B) radiographs of mid foot show multilocular osteolytic lesion expanding tarsal navicular bone medially with intact cortex.

 


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Fig. 4C. 26-year-old woman with lesion in tarsal navicular bone. T1-weighted coronal MR image (TR/TE, 500/17) shows complete replacement of tarsal navicular bone by tumor.

 


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Fig. 4D. 26-year-old woman with lesion in tarsal navicular bone. Fat-suppressed coronal MR image (4500/105) reveals no extraosseous mass. Tumor has multilocular appearance with high signal intensity and fluid-fluid levels.

 

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