AJR
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Abstract Freely available
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Georgian-Smith, D.
Right arrow Articles by Lawton, T. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Georgian-Smith, D.
Right arrow Articles by Lawton, T. J.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?

Calcifications of Lobular Carcinoma In Situ of the Breast

Radiologic—Pathologic Correlation

Dianne Georgian-Smith1 and Thomas J. Lawton2

1 Department of Radiology, University of Washington Medical Center, Box 357115, HSB RR-215, 1959 N.E. Pacific St., Seattle, WA 98195-7115.
2 Department of Pathology, University of Washington Medical Center, Seattle, WA 98195-6100.



View larger version (143K):

[in a new window]
  		Fig. 1A. —Classic lobular carcinoma in situ in 43-year-old woman. Photomicrograph of biopsy specimen shows calcifications (double arrows) in lobular carcinoma in situ and similar-appearing calcifications (single arrow) in focus of adenosis. (H and E, x100)

 


View larger version (152K):

[in a new window]
  		Fig. 2A. —Pleomorphic lobular carcinoma in situ in 34-year-old woman. Photomicrograph of biopsy specimen shows central necrosis and calcification (arrow) in lobule with lobular carcinoma in situ (arrowheads). (H and E, x400)

 


View larger version (160K):

[in a new window]
  		Fig. 2B. —Pleomorphic lobular carcinoma in situ in 34-year-old woman. Photomicrograph of biopsy specimen shows membranous staining of cells (solid arrows) in benign lobules with complete absence of staining of cells in lobular carcinoma in situ (open arrows). (E-cadherin immunostain, x100)

 


View larger version (126K):

[in a new window]
  		Fig. 2C. —Pleomorphic lobular carcinoma in situ in 34-year-old woman. Mammogram shows cluster of calcifications with three large (1 mm) pleomorphic calcifications (arrow) surrounded by punctate calcifications. Although no calcifications were branching in morphology, calcifications were thought to represent ductalcomedocarcinoma in situ. E-cadherin staining in (B) was significant in distinguishing lobular carcinoma in situ from ductal carcinoma in situ. (Spot magnification, x1.7)

 


View larger version (120K):

[in a new window]
  		Fig. 1B. —Classic lobular carcinoma in situ in 43-year-old woman. Mammogram shows cluster of punctate calcifications in lobular carcinoma in situ (arrow). Benign calcifications were in adjacent tissues (arrowheads). (Spot magnification, x1.7)

 


View larger version (129K):

[in a new window]
  		Fig. 3. —Mammogram of 58-year-old woman shows cluster of punctate calcifications (arrows) smaller than or equal to 0.5 mm. Appearance of calcifications was similar to that seen in all patients. Calcifications were in pleomorphic lobular carcinoma in situ.

 


View larger version (166K):

[in a new window]
  		Fig. 4. —Photomicrograph of biopsy specimen shows pleomorphic lobular carcinoma in situ with focus of infiltrating lobular carcinoma (double arrows) adjacent to lobular carcinoma in situ (single arrows). Cytologic features of cells in infiltrating lobular carcinoma were identical to cells in lobular carcinoma in situ. (H and E, x400)

 

Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?



HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2001 by the American Roentgen Ray Society.