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Value of Intraarterial Prostaglandin E1 Injection During CT Hepatic Arteriography

Takuji Yamagami1, Toshiyuki Nakamura1, Osamu Sato2, Yoshito Takeuchi3 and Tsunehiko Nishimura1

1 Department of Radiology, Kyoto Prefectural University of Medicine, 465 Kajii, Kawaramachi-Hirokoji, Kamigyo, Kyoto, 602-8566, Japan.
2 Department of Radiology, Akashi Municipal Hospital, 1-33, Takashyo, Akashi, Hyogo, 673-8501, Japan.
3 Department of Radiology, Kyoto First Red Cross Hospital, 5-749, Motomachi, Higashiyama, Kyoto, 605-0981, Japan.



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Fig. 1A. 47-year-old woman with metastatic breast cancer. Scan obtained from CT during arterial portography shows nontumorous defect of portal perfusion (arrow) in segment V of liver parenchyma adjacent to gallbladder.

 


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Fig. 1B. 47-year-old woman with metastatic breast cancer. CT hepatic arteriogram shows homogeneous wedge-shaped enhancing lesion (arrow) 12 mm in diameter corresponding to perfusion defect in liver parenchyma adjacent to gallbladder. Note that CT attenuation of enhancing lesion is 273 H.

 


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Fig. 1C. 47-year-old woman with metastatic breast cancer. CT hepatic arteriogram after prostaglandin E1 injection via superior mesenteric artery shows that size of enhanced area (arrow) around the gallbladder is decreased, with reduction rate being approximately 80% compared with that on CT hepatic arteriogram without prostaglandin E1. Note that CT attenuation, measured using same region-of-interest size and location as CT hepatic arteriogram without prostaglandin E1, is 213 H.

 


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Fig. 2A. 52-year-old man with hepatocellular carcinoma. CT scan obtained during arterial portography shows nontumorous decreased area of portal perfusion (arrow) in segment V around gallbladder.

 


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Fig. 2B. 52-year-old man with hepatocellular carcinoma. CT hepatic arteriogram shows wedge-shaped area of homogenous enhancement (arrow) measuring 20 mm in largest diameter, corresponding to defect of portal perfusion in segment V around gallbladder. CT attenuation of this enhancement on CT hepatic arteriography was 212 H.

 


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Fig. 2C. 52-year-old man with hepatocellular carcinoma. CT hepatic arteriogram after prostaglandin E1 injection shows that size and shape of nontumorous enhanced area are unchanged, but attenuation is decreased despite repeated administration of contrast material. CT attenuation value of this enhancement decreased to 160 H on CT hepatic arteriography after prostaglandin E1 injection.

 


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Fig. 3A. 55-year-old man with hepatocellular carcinoma. CT scan obtained during arterial portography shows tumorous defect of portal perfusion (arrow) in segment VI of liver.

 


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Fig. 3B. 55-year-old man with hepatocellular carcinoma. CT hepatic arteriogram shows round homogenous enhancement (arrow) 12 mm in diameter, corresponding to defect of portal perfusion.

 


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Fig. 3C. 55-year-old man with hepatocellular carcinoma. CT hepatic arteriogram obtained after prostaglandin E1 injection shows no change in size or shape of tumorous enhanced area.

 

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