Value of Intraarterial Prostaglandin E1 Injection During CT Hepatic Arteriography
Takuji Yamagami1,
Toshiyuki Nakamura1,
Osamu Sato2,
Yoshito Takeuchi3 and
Tsunehiko Nishimura1
1
Department of Radiology, Kyoto Prefectural University of Medicine, 465 Kajii,
Kawaramachi-Hirokoji, Kamigyo, Kyoto, 602-8566, Japan.
2
Department of Radiology, Akashi Municipal Hospital, 1-33, Takashyo, Akashi,
Hyogo, 673-8501, Japan.
3
Department of Radiology, Kyoto First Red Cross Hospital, 5-749, Motomachi,
Higashiyama, Kyoto, 605-0981, Japan.

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Fig. 1A. 47-year-old woman with metastatic breast cancer. Scan
obtained from CT during arterial portography shows nontumorous defect of
portal perfusion (arrow) in segment V of liver parenchyma adjacent to
gallbladder.
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Fig. 1B. 47-year-old woman with metastatic breast cancer. CT hepatic
arteriogram shows homogeneous wedge-shaped enhancing lesion (arrow)
12 mm in diameter corresponding to perfusion defect in liver parenchyma
adjacent to gallbladder. Note that CT attenuation of enhancing lesion is 273
H.
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Fig. 1C. 47-year-old woman with metastatic breast cancer. CT hepatic
arteriogram after prostaglandin E1 injection via superior
mesenteric artery shows that size of enhanced area (arrow) around the
gallbladder is decreased, with reduction rate being approximately 80% compared
with that on CT hepatic arteriogram without prostaglandin E1. Note
that CT attenuation, measured using same region-of-interest size and location
as CT hepatic arteriogram without prostaglandin E1, is 213 H.
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Fig. 2A. 52-year-old man with hepatocellular carcinoma. CT scan
obtained during arterial portography shows nontumorous decreased area of
portal perfusion (arrow) in segment V around gallbladder.
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Fig. 2B. 52-year-old man with hepatocellular carcinoma. CT hepatic
arteriogram shows wedge-shaped area of homogenous enhancement (arrow)
measuring 20 mm in largest diameter, corresponding to defect of portal
perfusion in segment V around gallbladder. CT attenuation of this enhancement
on CT hepatic arteriography was 212 H.
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Fig. 2C. 52-year-old man with hepatocellular carcinoma. CT hepatic
arteriogram after prostaglandin E1 injection shows that size and
shape of nontumorous enhanced area are unchanged, but attenuation is decreased
despite repeated administration of contrast material. CT attenuation value of
this enhancement decreased to 160 H on CT hepatic arteriography after
prostaglandin E1 injection.
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Fig. 3A. 55-year-old man with hepatocellular carcinoma. CT scan
obtained during arterial portography shows tumorous defect of portal perfusion
(arrow) in segment VI of liver.
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Fig. 3B. 55-year-old man with hepatocellular carcinoma. CT hepatic
arteriogram shows round homogenous enhancement (arrow) 12 mm in
diameter, corresponding to defect of portal perfusion.
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Fig. 3C. 55-year-old man with hepatocellular carcinoma. CT hepatic
arteriogram obtained after prostaglandin E1 injection shows no
change in size or shape of tumorous enhanced area.
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Copyright © 2001 by the American Roentgen Ray Society.