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Posttransplantation Non-Hodgkin's Lymphoma of the Adrenal Gland

Mark E. Mullins1, Steven Chao1, Henry Dong2 and Priscilla J. Slanetz1

1 Department of Radiology, Massachusetts General Hospital, Founders House, Boston, MA 02114.
2 Department of Pathology, Massachusetts General Hospital, Boston, MA 02114.



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  		Fig. 1A. —59-year-old man, who presented 8 years after heart transplantation, with right adrenal mass pathologically proven to be B-cell lymphoma. Contrast-enhanced CT image shows round right adrenal mass (arrow) measuring 78 H in attenuation.

 


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  		Fig. 1B. —59-year-old man, who presented 8 years after heart transplantation, with right adrenal mass pathologically proven to be B-cell lymphoma. High-resolution photomicrograph of pathology specimen shows diffuse proliferation of large, atypical lymphocytes with irregular nuclear contours, frequently prominent nucleoli, and high mitotic rate. (H and E, x200)

 


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  		Fig. 1C. —59-year-old man, who presented 8 years after heart transplantation, with right adrenal mass pathologically proven to be B-cell lymphoma. High-resolution photomicrograph of pathology specimen shows many tumor cells express Epstein-Barr virus-encoded RNA detected by in situ hybridization as darkly stained nuclei. (Immunoperoxidase, x200)

 

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