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Quantification of Coronary Artery Calcium Using Multidetector CT and a Retrospective ECG-Gating Reconstruction Algorithm

Jun Horiguchi1, Tadashi Nakanishi2 and Katsuhide Ito1

1 Department of Radiology, Hiroshima University School of Medicine, 1-2-3, Kasumi-cho, Minami-ku, Hiroshima, 734-8551, Japan
2 Department of Radiology, Mazda Hospital, 2-15, Aosakiminami, Huchu-cho, Aki-gun, Hiroshima, 735-0017, Japan.



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Fig. 1. Drawing shows method of ECG-gated data acquisition on multisector reconstructions. Images of arbitrary phase of cardiac cycles can be reconstructed with retrospective ECG-gated technique. Note that diastolic data (sectors) have been collected from four consecutive cardiac cycles.

 


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Fig. 2. Graph shows that temporal resolution of multisector varies according to heart rate. Here, temporal resolution values of multisector reconstruction are shown at gantry rotation speeds of 0.8 and 1.0 sec per rotation. bpm = beats per minute.

 


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Fig. 3. CT scan of 38-year-old healthy male volunteer shows peak CT value measurement in course of coronary artery. For all 55 coronary arteries without calcified deposits, we extracted most peripherally possible pixels encompassing left main artery, left anterior descending artery, and pericoronary fat tissue on workstation and then gathered them into voxel. Then we measured peak CT value in voxel.

 


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Fig. 4. Scatterplot shows total calcium scores derived using electron beam CT and multidetector CT with single-sector reconstruction with threshold of 90 H. Total calcium scores were obtained using modified Agatston method for multidetector CT. Note calcium scores show low agreement in high scores.

 


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Fig. 5. Scatterplot shows total calcium scores using electron beam CT and multidetector CT with singlesector reconstruction with threshold of 130 H. Total calcium scores were obtained using Agatston method for both CT techniques.

 


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Fig. 6. Scatterplot shows total calcium scores using electron beam CT and multidetector CT with multisector reconstruction with threshold of 90 H. Note calcium scores show high correlation with wide range of scores.

 


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Fig. 7. Scatterplot shows total calcium scores using electron beam CT and multidetector CT with multisector reconstruction with threshold of 130 H. Note calcium scores show high correlation with wide range of scores.

 


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Fig. 8A. 40-year-old obese man with coronary artery calcification (heart rate = 41 beats per minute). Axial electron beam CT scan reveals calcified deposits that are obscured by marked interference of streaking artifacts.

 


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Fig. 8B. 40-year-old obese man with coronary artery calcification (heart rate = 41 beats per minute). Multisector reconstruction of axial multidetector CT scan (temporal resolution, 137 msec) shows calcification of right coronary artery.

 


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Fig. 9A. 57-year-old man with coronary artery calcification (heart rate = 74 beats per minute). Axial electron beam CT scan shows arc-shaped artifact from calcification of right coronary artery.

 


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Fig. 9B. 57-year-old man with coronary artery calcification (heart rate = 74 beats per minute). Multisector reconstruction of axial multidetector CT scan (temporal resolution, 500 msec) shows artifacts from calcification are more pronounced.

 

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