Calcium Scoring of the Coronary Artery by Electron Beam CT
How to Apply an Individual Attenuation Threshold
Paolo Raggi1,
Tracy Q. Callister2 and
Bruce Cooil3
1
Tulane University School of Medicine, Cardiology Section, SL48, 1430 Tulane
Ave., New Orleans, LA 70112.
2
EBT Research Foundation, 353 New Shackle Island Rd., Hendersonville, TN
37025.
3
Owen Graduate School of Management, Vanderbilt University, 401 21st Ave. S.
Nashville, TN 37203.

View larger version (135K):
[in a new window]
|
Fig. 1A. Axial electron beam CT scans of chest obtained in 74-year-old
woman at level of proximal to middle portion of left anterior descending
coronary artery show calcification. Computer software automatically highlights
all pixels, with CT number > 130 H in yellow. Along with calcification of
left anterior descending coronary artery (in white rectangle), substantial
image noise (scattered yellow pixels) is also seen.
|
|

View larger version (125K):
[in a new window]
|
Fig. 1B. Axial electron beam CT scans of chest obtained in 74-year-old
woman at level of proximal to middle portion of left anterior descending
coronary artery show calcification. Computer software automatically highlights
all pixels, with CT number > 130 H in yellow. After calculation of optimal
attenuation threshold by adding 3 standard deviations (SD) to measured mean
soft-tissue CT number, background noise disappears. In this example, mean
soft-tissue CT number is 45 H with SD of 40 H, and calculated optimal
threshold is 165 H.
|
|

View larger version (13K):
[in a new window]
|
Fig. 2. Box plots of mean soft-tissue attenuation measured at level
of origin of left main coronary artery (high-level mean) and at level of
diaphragm (low-level mean).
|
|

View larger version (12K):
[in a new window]
|
Fig. 3. Box plots of standard deviation (SD) of soft-tissue
attenuation measured at level of origin of left main coronary artery
(high-level SD) and at level of diaphragm (low-level SD).
|
|

View larger version (11K):
[in a new window]
|
Fig. 4. Correlation between soft-tissue attenuation measurements made
at bottom of heart (low level) and body weight in all 48 patients. As body
weight increases, mean soft-tissue attenuation decreases and standard
deviation increases.
|
|

View larger version (12K):
[in a new window]
|
Fig. 5. Correlation between ideal threshold (mean soft-tissue CT
number plus 3 standard deviations [SD]) at bottom of heart (low level) and
patient's body weight. As body weight increases, ideal soft-tissue attenuation
increases as function of increasing SD (y = 0.4839x +
26.179).
|
|

CiteULike
Complore
Connotea
Del.icio.us
Digg
Reddit
Technorati What's this?
Copyright © 2002 by the American Roentgen Ray Society.