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Dual-Phase Helical CT of Pancreatic Adenocarcinoma

Assessment of Resectability Before Surgery

Carlos Valls1, Eduard Andía1, Anna Sanchez1, Juan Fabregat2, Oscar Pozuelo1, Juan Carlos Quintero1, Teresa Serrano3, Francisco Garcia-Borobia2 and Rosa Jorba2

1 Institut de Diagnòstic per la Imatge, Hospital Duran i Reynals, Ciutat Sanitària i Universitària de Bellvitge, Autovia de Castelldefels km 2, 7, L'Hospitalet de Llobregat, 08907 Barcelona, Spain.
2 Department of Surgery, Hospital Princeps d'Espanya Ciutat Sanitaria i Universitaria de Bellvitge, C/Feixa Llarga s/n, L'Hospitalet de Llobregat, 08907 Barcelona, Spain.
3 Department of Pathology, Hospital Princeps d'Espanya, 08907 Barcelona, Spain.



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Fig. 1. Arterial invasion in 65-year-old woman with obstructive jaundice. Helical CT scan shows large hypodense mass (arrow) in pancreatic head, abutting and encasing superior mesenteric artery. This sign is clear indication of unresectability, and patient was excluded from surgery.

 


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Fig. 2. Helical CT scan obtained during pancreatic phase in 52-year-old man reveals small hypoattenuating mass (arrow) in pancreatic head. Tumor abuts superior mesenteric vein (arrowhead), but tumor-to-vessel circumferential contiguity is less than 50%, indicating absence of venous invasion. Surgical exploration confirmed absence of venous invasion, and tumor was resected without venous resection.

 


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Fig. 3A. 78-year-old woman with unresectable pancreatic cancer understaged using helical CT. Note small hepatic cyst (arrowhead) in both pancreatic and portal phases. Pancreatic-phase CT scan shows small hypervascular hepatic lesion (arrow) in segment III that was missed at prospective evaluation.

 


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Fig. 3B. 78-year-old woman with unresectable pancreatic cancer understaged using helical CT. Note small hepatic cyst (arrowhead) in both pancreatic and portal phases. During portal phase, CT scan obtained at same level as A shows lesion is isoattenuating and no longer visible.

 


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Fig. 4. 61-year-old man who had pancreatic adenocarcinoma with venous invasion. Axial helical CT image obtained at level of uncinate process shows large hypodense mass (arrow) with circumferential involvement of superior mesenteric vein. Note that tumor-to-vein contiguity (arrowheads) is greater than 50%, indicating venous invasion. Tumor was successfully resected after en bloc venous resection and terminoterminal anastomosis.

 


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Fig. 5. Axial CT scan in 69-year-old woman shows low-density tumor (arrow) in pancreatic head. Tumor-to-vein contiguity is less than 50%, suggesting absence of venous invasion. However at surgical exploration, venous invasion was found, and tumor was resected with partial vein resection.

 


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Fig. 6. Periarterial streaks in resectable pancreatic adenocarcinoma in 61-year-old woman with obstructive jaundice. Transverse contrast-enhanced CT scan reveals low-density lesion (arrow) in pancreatic head. Note periarterial streaks (arrowhead) arising from tumor and in contact with lateral aspect of superior mesenteric artery.

 


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Fig. 7. Periarterial streaks in unresectable pancreatic adenocarcinoma in 66-year-old man with obstructive jaundice. Helical CT scan shows hypodense lesion (arrow) in uncinate process and linear reticular opacities arising from tumor and abutting posterior aspect of superior mesenteric artery (arrowhead). At surgical exploration, invasion of mesenteric artery was found. Resection was not possible, leaving grossly positive margin.

 

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