Intramuscular Myxoma
Characteristic MR Imaging Features
Laura W. Bancroft1,
Mark J. Kransdorf1,
David M. Menke2,
Mary I. O'Connor3 and
William C. Foster4
1 Department of Radiology, Mayo Clinic, 4500 San Pablo Rd., Jacksonville, FL
32224-3899.
2 Department of Pathology, Mayo Clinic, Jacksonville, FL 32224-3899.
3 Department of Orthopedic Surgery, Mayo Clinic, Jacksonville, FL
32224-3899.
4 Department of Orthopedic Surgery, Medical College of Virginia, Virginia
Commonwealth University, 1200 E. Broad St., P. O. Box 980153, Richmond, VA
23298.
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Fig. 1A. —Intramuscular myxoma in adductor compartment of left thigh in
69-year-old man. Coronal T1-weighted spin-echo MR image (TR/TE, 400/20) shows
rind of adipose tissue with varying thickness surrounding ovoid, homogeneously
hypointense lesion (asterisk).
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Fig. 1B. —Intramuscular myxoma in adductor compartment of left thigh in
69-year-old man. Comparison of unenhanced (B) and enhanced (C)
corresponding axial T1-weighted spin-echo MR images (400/20) shows prominent
heterogeneous enhancement. Rind of adipose tissue is seen to better advantage
on long-axis coronal image (A) rather than on axial image
(B).
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Fig. 1C. —Intramuscular myxoma in adductor compartment of left thigh in
69-year-old man. Comparison of unenhanced (B) and enhanced (C)
corresponding axial T1-weighted spin-echo MR images (400/20) shows prominent
heterogeneous enhancement. Rind of adipose tissue is seen to better advantage
on long-axis coronal image (A) rather than on axial image
(B).
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Fig. 1D. —Intramuscular myxoma in adductor compartment of left thigh in
69-year-old man. Axial T2-weighted MR image (1800/80) obtained at same level
as A shows slightly increased signal in muscle adjacent to mass
(arrow).
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Fig. 2A. —Intramuscular myxoma in vastus medialis of left thigh of
85-year-old woman. Coronal T1-weighted spin-echo MR image (TR/TE, 500/15)
reveals subtle rind of adipose tissue at periphery of heterogeneous ovoid
lesion.
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Fig. 2B. —Intramuscular myxoma in vastus medialis of left thigh of
85-year-old woman. Axial T1-weighted spin-echo MR image (600/15) at mid
portion (asterisk) of lesion depicts heterogeneously hypointense and
isotense signal intensity of lesion.
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Fig. 2C. —Intramuscular myxoma in vastus medialis of left thigh of
85-year-old woman. Obtained at more inferior position than B, this
axial T1-weighted MR image allows easier appreciation of rind (arrow)
of adipose tissue at inferior aspect of lesion. However, in axial plane,
contour of rind may appear to be intermuscular fat rather than interface
between lesion and surrounding muscle.
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Fig. 2D. —Intramuscular myxoma in vastus medialis of left thigh of
85-year-old woman. Coronal short tau inversion recovery MR image (2000/20;
inversion time, 150 msec) shows markedly hyperintense signal in myxoma as well
as in adjacent skeletal muscle.
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Fig. 2E. —Intramuscular myxoma in vastus medialis of left thigh of
85-year-old woman. Axial T2-weighted spin-echo MR image (2000/80) obtained 10
mm inferior to level at which B was obtained at very inferior margin of
lesion (asterisk), shows extensive increased signal in adjacent
skeletal muscle.
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Fig. 2F. —Intramuscular myxoma in vastus medialis of left thigh of
85-year-old woman. Axial T1-weighted MR image (600/15) obtained after
injection of contrast material shows prominent heterogeneous enhancement
(arrows).
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Fig. 3A. —Intramuscular myxoma in right adductor compartment in
76-year-old man. Coronal T1-weighted MR image (TR/TE, 665/15) displays
heterogeneous low and intermediate signal intensity of myxoma.
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Fig. 3B. —Intramuscular myxoma in right adductor compartment in
76-year-old man. Corresponding coronal T2-weighted fast spin-echo MR image
(5150/125) exhibits primarily hyperintense lesion, with hypointense septal and
nodular foci.
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Fig. 4A. —Photomicrographs of intramuscular myxoma in 77-year-old
woman. Infiltration of myxoma (asterisk) into adjacent skeletal
muscle (arrows) is visible. Myxoma is composed of scanty, poorly
outlined cells in mucoid basophilic matrix and lacks distinct capsule. (H and
E, x100)
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Fig. 4B. —Photomicrographs of intramuscular myxoma in 77-year-old
woman. Myxoma (black asterisk) seen on left lacks distinct capsule
and is separated by condensed fibrous matrix (white asterisk) from
atrophic and adipose-replaced skeletal muscle on right. (H and E,
x40)
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Copyright © 2002 by the American Roentgen Ray Society.
