HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Abstract Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Mahnken, A. H. Articles by Günther, R. W. Search for Related Content PubMed PubMed Citation Articles by Mahnken, A. H. Articles by Günther, R. W. Social Bookmarking                      What's this? Hotlight (NEW!) What's Hotlight?

Multidetector CT of the Spine in Multiple Myeloma: Comparison with MR Imaging and Radiography

¹ Department of Radiology, University Hospital, University of Technology, Pauwelsstr. 30, D-52074 Aachen, Germany.
² Medical Clinic IV, University Hospital, University of Technology, D-52074 Aachen, Germany.

View larger version (69K): [in a new window]   Fig. 1A. —77-year-old man with multiple myeloma stage III according to criteria of Durie and Salmon [6]. Lateral radiograph of lumbar spine shows multiple myeloma affecting L2-L4.

View larger version (83K): [in a new window]   Fig. 1B. —77-year-old man with multiple myeloma stage III according to criteria of Durie and Salmon [6]. Sagittal reformation of multidetector CT data set depicts diffuse osteopenia and focal lesions as signs of multiple myeloma infiltration of entire spine. Focal lesion close to end plate of L1 (arrows) is not visible on conventional radiograph (A).

View larger version (99K): [in a new window]   Fig. 1C. —77-year-old man with multiple myeloma stage III according to criteria of Durie and Salmon [6]. Sagittal T1-weighted MR image (TR/TE, 487/20) shows multiple myeloma infiltration of entire spine, including lesion of L1 (arrows).

View larger version (71K): [in a new window]   Fig. 2A. —68-year-old man with newly diagnosed multiple myeloma, stage III according to criteria of Durie and Salmon [6]. Lateral radiograph of lumbar spine corresponding to multidetector CT (MDCT) and MR image shows large osteolytic lesion affecting posterior crest of L5 (arrows). Further lesions larger than 1 cm in diameter in lumbar spine and in T3 and T9 are not recognizable on conventional radiographs.

View larger version (76K): [in a new window]   Fig. 2B. —68-year-old man with newly diagnosed multiple myeloma, stage III according to criteria of Durie and Salmon [6]. MDCT scan depicts lesions with diameter greater than 10 mm in L5 (arrows) as well as in L1—L4, T3, and T9 (arrowheads). Diffuse osteopenia or lesions with diameters between 5 mm and 1 cm are visible in all vertebrae depicted. Ground-plate impression is visible in L1.

View larger version (64K): [in a new window]   Fig. 2C. —68-year-old man with newly diagnosed multiple myeloma, stage III according to criteria of Durie and Salmon [6]. Sagittal T2-weighted MR image (TR/TE, 2957/120; echo-train length, 13) shows tumor infiltration of all depicted vertebrae. Lesions larger than 1 cm in lumbar spine (arrowheads), especially in L5 (arrow), are clearly depicted.

View larger version (118K): [in a new window]   Fig. 3A. —77-year-old man with lengthy history of multiple myeloma. Radiograph of pelvis depicts large osteolysis of right iliac bone (arrows), including iliac crest. Osteosynthesis was performed on left side after pathologic fracture of left femoral neck due to multiple myeloma infiltration.

View larger version (94K): [in a new window]   Fig. 3B. —77-year-old man with lengthy history of multiple myeloma. Multiplanar reformation of multidetector CT data set reveals destruction of right acetabulum (straight arrows) and smaller metastatic lesion of left acetabulum (asterisk). Osteolysis of right iliac bone is visible (curved arrows). Additional metastasis of left iliac bone (arrowheads), not seen on conventional radiograph (A), is evident.

View larger version (63K): [in a new window]   Fig. 4A. —68-year-old man with history of multiple myeloma, stage III according to criteria of Durie and Salmon [6]. Lateral radiograph of lumbar spine shows several lytic bone lesions, one in L5 (arrow).

View larger version (84K): [in a new window]   Fig. 4B. —68-year-old man with history of multiple myeloma, stage III according to criteria of Durie and Salmon [6]. Same lesion in L5 is visible on multiplanar reformation calculated from multidetector CT data set (arrow).

View larger version (88K): [in a new window]   Fig. 4C. —68-year-old man with history of multiple myeloma, stage III according to criteria of Durie and Salmon [6]. Sagittal T1-weighted MR image (TR/TE, 48/20) depicts homogeneous signal of L5 with no focal lesion.

View larger version (69K): [in a new window]   Fig. 5A. —82-year-old woman with multiple myeloma, stage III according to criteria of Durie and Salmon [6]. Lateral radiograph of thoracic spine shows diffuse osteopenia of all vertebrae.

View larger version (91K): [in a new window]   Fig. 5B. —82-year-old woman with multiple myeloma, stage III according to criteria of Durie and Salmon [6]. Radiograph of lumbar spine presents same finding as A.

View larger version (65K): [in a new window]   Fig. 5C. —82-year-old woman with multiple myeloma, stage III according to criteria of Durie and Salmon [6]. Sagittal multiplanar reformation of lumbar and thoracic spine calculated from multidetector CT data set also depicts diffuse osteopenia. Some lesions larger than 5 mm but smaller than 1 cm are also visible.

View larger version (51K): [in a new window]   Fig. 5D. —82-year-old woman with multiple myeloma, stage III according to criteria of Durie and Salmon [6]. Sagittal T1-weighted MR image (TR/TE, 487/20) depicts diffuse tumor infiltration of all lumbar and thoracic vertebrae.

View larger version (55K): [in a new window]   Fig. 5E. —82-year-old woman with multiple myeloma, stage III according to criteria of Durie and Salmon [6]. After administration of gadopentetate dimeglumine, sagittal T1-weighted MR image (487/20) of thoracic and lumbar vertebrae shows diffuse contrast enhancement.

CiteULike

Complore

Connotea

Del.icio.us

Digg

Reddit

Technorati