Reliability of MR ImagingBased Virtual Cystoscopy in the Diagnosis of Cancer of the Urinary Bladder
Markus Lämmle1,2,
Ambros Beer1,
Marcus Settles1,
Christian Hannig1,
Hartwig Schwaibold3 and
Carsten Drews3
1 Department of Radiology, Klinikum rechts der Isar der Technischen
Universität München, Ismaninger Str. 22, D-81675 Munich,
Germany.
2 Present address: Division of Diagnostic Radiology, Mallinckrodt Institute of
Radiology, Washington University School of Medicine, 510 S. Kingshighway
Blvd., St. Louis, MO 63110.
3 Department of Urology, Klinikum rechts der Isar der Technischen
Universität München, D-81675 Munich, Germany.

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Fig. 1. Histogram depicts number of tumors found per patient. Left
columns (gray) represent cystoscopy, and right columns (white) represent
virtual endoscopy. Findings on conventional cystoscopy revealed that 17
patients had single bladder tumor, five had two tumors, and two had three
tumors.
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Fig. 2. Histogram depicts number of tumors found on cystoscopy (gray
columns) and virtual endoscopy (white columns) and their diameters. All known
tumors of 1 cm and larger were seen on virtual endoscopy. All three tumors not
identified on virtual endoscopy were smaller than 1 cm in diameter. Two tumors
not discovered on cystoscopy but detected by virtual endoscopy are included in
corresponding columns.
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Fig. 3A. 62-year-old man with primary urinary bladder cancer.
Anteroposterior virtual endoscopic image depicts posterior bladder wall and
vesical trigone. The trigone is demarcated by two ureteric orifices
(arrowheads) and internal urethral orifice (arrow). Marked
prostatic protrusion visible in foreground is consistent with prostatic
hypertrophy.
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Fig. 3B. 62-year-old man with primary urinary bladder cancer. Virtual
endoscopic intravesical image of anterior bladder wall (posteroanterior view:
field of view, 90°) depicts two papillary tumors (arrowheads) 0.8
and 1.4 cm in diameter at left anterior bladder wall and right ventral
dome.
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Fig. 4A. 45-year-old woman with recurrent urinary bladder cancer.
Virtual endoscopic images of four bladder wall diverticula before zooming
(A) and after zooming (B) show tumor at neck of one diverticulum
(arrow). Tumor diameter is 0.4 cmone of smallest found in our
study.
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Fig. 4B. 45-year-old woman with recurrent urinary bladder cancer.
Virtual endoscopic images of four bladder wall diverticula before zooming
(A) and after zooming (B) show tumor at neck of one diverticulum
(arrow). Tumor diameter is 0.4 cmone of smallest found in our
study.
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Fig. 5A. 64-year-old man with solitary urinary bladder tumor.
Conventional cystoscopic image (A) and virtual endoscopic image
(B: field of view, 30°) depict tumor 2.3 cm in diameter.
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Fig. 5B. 64-year-old man with solitary urinary bladder tumor.
Conventional cystoscopic image (A) and virtual endoscopic image
(B: field of view, 30°) depict tumor 2.3 cm in diameter.
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Fig. 5C. 64-year-old man with solitary urinary bladder tumor. Coronal
T2-weighted MR image (C) and virtual endoscopic image with overall view
(D, 120°) show tumor's location next to vesical trigone
ventrolateral to left ureteric orifice. Internal urethral orifice can be
identified in lower mid portion of D.
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Fig. 5D. 64-year-old man with solitary urinary bladder tumor. Coronal
T2-weighted MR image (C) and virtual endoscopic image with overall view
(D, 120°) show tumor's location next to vesical trigone
ventrolateral to left ureteric orifice. Internal urethral orifice can be
identified in lower mid portion of D.
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Fig. 6A. 60-year-old man with primary urinary bladder cancer. Coronal
T2-weighted MR image shows two lesions (arrows) in right and left
lower part of bladder in area of vesical trigone.
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Fig. 6B. 60-year-old man with primary urinary bladder cancer. Virtual
endoscopic image focused on vesical trigone reveals that only one tumor is
present (1.4 cm in diameter, arrow). Tumor is located near left
ureteric orifice. Structure seen on right side in coronal T2-weighted image
(A) is identified on virtual endoscopic image as part of normal vesical
trigone and not tumor. Internal urethral orifice can be identified in lower
mid portion.
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