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Reliability of MR Imaging—Based Virtual Cystoscopy in the Diagnosis of Cancer of the Urinary Bladder

Markus Lämmle1,2, Ambros Beer1, Marcus Settles1, Christian Hannig1, Hartwig Schwaibold3 and Carsten Drews3

1 Department of Radiology, Klinikum rechts der Isar der Technischen Universität München, Ismaninger Str. 22, D-81675 Munich, Germany.
2 Present address: Division of Diagnostic Radiology, Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 S. Kingshighway Blvd., St. Louis, MO 63110.
3 Department of Urology, Klinikum rechts der Isar der Technischen Universität München, D-81675 Munich, Germany.



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Fig. 1. Histogram depicts number of tumors found per patient. Left columns (gray) represent cystoscopy, and right columns (white) represent virtual endoscopy. Findings on conventional cystoscopy revealed that 17 patients had single bladder tumor, five had two tumors, and two had three tumors.

 


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Fig. 2. Histogram depicts number of tumors found on cystoscopy (gray columns) and virtual endoscopy (white columns) and their diameters. All known tumors of 1 cm and larger were seen on virtual endoscopy. All three tumors not identified on virtual endoscopy were smaller than 1 cm in diameter. Two tumors not discovered on cystoscopy but detected by virtual endoscopy are included in corresponding columns.

 


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Fig. 3A. 62-year-old man with primary urinary bladder cancer. Anteroposterior virtual endoscopic image depicts posterior bladder wall and vesical trigone. The trigone is demarcated by two ureteric orifices (arrowheads) and internal urethral orifice (arrow). Marked prostatic protrusion visible in foreground is consistent with prostatic hypertrophy.

 


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Fig. 3B. 62-year-old man with primary urinary bladder cancer. Virtual endoscopic intravesical image of anterior bladder wall (posteroanterior view: field of view, 90°) depicts two papillary tumors (arrowheads) 0.8 and 1.4 cm in diameter at left anterior bladder wall and right ventral dome.

 


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Fig. 4A. 45-year-old woman with recurrent urinary bladder cancer. Virtual endoscopic images of four bladder wall diverticula before zooming (A) and after zooming (B) show tumor at neck of one diverticulum (arrow). Tumor diameter is 0.4 cm—one of smallest found in our study.

 


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Fig. 4B. 45-year-old woman with recurrent urinary bladder cancer. Virtual endoscopic images of four bladder wall diverticula before zooming (A) and after zooming (B) show tumor at neck of one diverticulum (arrow). Tumor diameter is 0.4 cm—one of smallest found in our study.

 


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Fig. 5A. 64-year-old man with solitary urinary bladder tumor. Conventional cystoscopic image (A) and virtual endoscopic image (B: field of view, 30°) depict tumor 2.3 cm in diameter.

 


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Fig. 5B. 64-year-old man with solitary urinary bladder tumor. Conventional cystoscopic image (A) and virtual endoscopic image (B: field of view, 30°) depict tumor 2.3 cm in diameter.

 


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Fig. 5C. 64-year-old man with solitary urinary bladder tumor. Coronal T2-weighted MR image (C) and virtual endoscopic image with overall view (D, 120°) show tumor's location next to vesical trigone ventrolateral to left ureteric orifice. Internal urethral orifice can be identified in lower mid portion of D.

 


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Fig. 5D. 64-year-old man with solitary urinary bladder tumor. Coronal T2-weighted MR image (C) and virtual endoscopic image with overall view (D, 120°) show tumor's location next to vesical trigone ventrolateral to left ureteric orifice. Internal urethral orifice can be identified in lower mid portion of D.

 


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Fig. 6A. 60-year-old man with primary urinary bladder cancer. Coronal T2-weighted MR image shows two lesions (arrows) in right and left lower part of bladder in area of vesical trigone.

 


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Fig. 6B. 60-year-old man with primary urinary bladder cancer. Virtual endoscopic image focused on vesical trigone reveals that only one tumor is present (1.4 cm in diameter, arrow). Tumor is located near left ureteric orifice. Structure seen on right side in coronal T2-weighted image (A) is identified on virtual endoscopic image as part of normal vesical trigone and not tumor. Internal urethral orifice can be identified in lower mid portion.

 

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