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MR Imaging of Large Multinodular Goiters: Observer Agreement on Volume Versus Observer Disagreement on Dimensions of the Involved Trachea

Steen J. Bonnema1, Peter B. Andersen2, Dorthe U. Knudsen2 and Laszlo Hegedüs1

1 Department of Endocrinology, Odense University Hospital, DK-5000 Odense, Denmark.
2 Department of Radiology, Odense University Hospital, DK-5000 Odense, Denmark.



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Fig. 1A. 85-year-old woman with large multinodular goiter. Coronal T1-weighted MR image shows compression of trachea (white arrow) and left-sided substernal extension (black arrows).

 


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Fig. 1B. 85-year-old woman with large multinodular goiter. Axial T1-weighted MR images show marked contours of goiter (B) and tracheal lumen (C).

 


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Fig. 1C. 85-year-old woman with large multinodular goiter. Axial T1-weighted MR images show marked contours of goiter (B) and tracheal lumen (C).

 


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Fig. 2. Graph shows intraobserver difference of two measurements (difference plot) of goiter volume. Solid line indicates mean value of all measurements (n = 68), and dotted lines denote 95% limits of agreement (mean ± 1.96 SD).

 


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Fig. 3. Graph shows interobserver difference of two measurements (difference plot) of goiter volume. Solid line indicates mean value of all measurements (n = 68), and dotted lines denote 95% limits of agreement (mean ± 1.96 SD).

 


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Fig. 4. Graph shows interobserver difference of two measurements (difference plot) of smallest crosssectional area of trachea. Solid line indicates mean value of all measurements (n = 68), and dotted lines denote 95% limits of agreement (mean ± 1.96 SD).

 


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Fig. 5. Graph shows interobserver difference of two measurements (difference plot) of tracheal volume along initial goiter extension. Solid line indicates mean value of all measurements (n = 68), and dotted lines denote 95% limits of agreement (mean ± 1.96 SD).

 


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Fig. 6. Graph shows intraobserver correlation of measurements (n = 68) of goiter volume. Regression line is shown.

 


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Fig. 7. Graph shows interobserver correlation of measurements (n = 68) of goiter volume. Regression line is shown.

 


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Fig. 8. Graph shows interobserver correlation of measurements (n = 68) of smallest cross-sectional area of trachea. Regression line is shown.

 


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Fig. 9. Graph shows interobserver correlation of measurements (n = 68) of tracheal volume along initial goiter extension. Regression line is shown.

 


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Fig. 10. Graph shows difference between MR imaging and sonographic goiter volume measurements (difference plot). Solid line indicates mean value of all measurements (n = 24), and dotted lines denote 95% limits of agreement (mean ± 1.96 SD).

 


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Fig. 11. Graph shows correlation between MR imaging and sonographic goiter volume measurements (n = 24). Regression line is shown. [Volume on sonography=-10.3 mL + (0.93xvolume on MR imaging)] r=0.93, p<0.001.

 

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