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Multidetector CT: Diagnostic Impact of Slice Thickness on Detection of Hypervascular Hepatocellular Carcinoma

Shuji Kawata1, Takamichi Murakami1, Tonsok Kim1, Masatoshi Hori1, Michael P. Federle2, Seishi Kumano1, Eiji Sugihara1, Shigeru Makino1, Hironobu Nakamura1 and Masayuki Kudo3

1 Department of Radiology, Osaka University Graduate School of Medicine D1, 2-2 Yamadaoka, Suita City, Osaka, 565-0871 Japan.
2 Department of Radiology, University of Pittsburgh Medical Center, 200 Lothrop St, Pittsburgh, PA 15213.
3 General Electric Yokogawa Medical Systems, 7-127 Asahigaoka 4-chome, Hino City, Tokyo, 191-8503 Japan.



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  		Fig. 1. —Bar chart shows number of lesions detected by each of three observers on images obtained with different slice thicknesses. Note interobserver agreement is substantial for 2.5- and 7.5-mm slice thicknesses and moderate for 5-mm slice thickness. Black bars = observer 1, white bars = observer 2, gray bars = observer 3.

 


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  		Fig. 2A. —Hypervascular hepatocellular carcinoma nodule, 14 mm in diameter, in 71-year-old man. CT scans obtained in late arterial phase with slice thicknesses of 2.5 (A), 5 (B), and 7.5 mm (C) show hypervascular tumor (arrow). Note lesion is conspicuous at each slice thickness.

 


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  		Fig. 2B. —Hypervascular hepatocellular carcinoma nodule, 14 mm in diameter, in 71-year-old man. CT scans obtained in late arterial phase with slice thicknesses of 2.5 (A), 5 (B), and 7.5 mm (C) show hypervascular tumor (arrow). Note lesion is conspicuous at each slice thickness.

 


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  		Fig. 2C. —Hypervascular hepatocellular carcinoma nodule, 14 mm in diameter, in 71-year-old man. CT scans obtained in late arterial phase with slice thicknesses of 2.5 (A), 5 (B), and 7.5 mm (C) show hypervascular tumor (arrow). Note lesion is conspicuous at each slice thickness.

 


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  		Fig. 3A. —Hypervascular hepatocellular carcinoma nodule, 8 mm in diameter, in 74-year-old man. CT scans obtained in late arterial phase with slice thickness of 2.5 (A), 5 (B), and 7.5 mm (C) show hypervascular tumor (arrow). Hypervascular nodule in lateral segment (arrow) is conspicuous on images obtained with 2.5- (A) and 5-mm (B) slice thickness, whereas lesion is very subtle on image obtained with 7.5-mm (C) slice thickness because of partial volume effect.

 


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  		Fig. 3B. —Hypervascular hepatocellular carcinoma nodule, 8 mm in diameter, in 74-year-old man. CT scans obtained in late arterial phase with slice thickness of 2.5 (A), 5 (B), and 7.5 mm (C) show hypervascular tumor (arrow). Hypervascular nodule in lateral segment (arrow) is conspicuous on images obtained with 2.5- (A) and 5-mm (B) slice thickness, whereas lesion is very subtle on image obtained with 7.5-mm (C) slice thickness because of partial volume effect.

 


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  		Fig. 3C. —Hypervascular hepatocellular carcinoma nodule, 8 mm in diameter, in 74-year-old man. CT scans obtained in late arterial phase with slice thickness of 2.5 (A), 5 (B), and 7.5 mm (C) show hypervascular tumor (arrow). Hypervascular nodule in lateral segment (arrow) is conspicuous on images obtained with 2.5- (A) and 5-mm (B) slice thickness, whereas lesion is very subtle on image obtained with 7.5-mm (C) slice thickness because of partial volume effect.

 

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