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Hemodynamic Characterization of Focal Nodular Hyperplasia Using Three-Dimensional Volume-Rendered Multidetector CT Angiography

Giuseppe Brancatelli1,2, Michael P. Federle1, Sanjeev Katyal1 and Vibhu Kapoor1

1 Department of Radiology, Division of Abdominal Imaging, University of Pittsburgh Medical Center, 200 Lothrop St., Pittsburgh, PA 15213.
2 Present address: Department of Radiology, University of Palermo, Italy.



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Fig. 1A. 39-year-old woman with focal nodular hyperplasia. Early hepatic arterial phase transverse CT scan (20-sec delay) shows large homogeneously and brightly enhancing mass (solid straight arrow) with central scar (open arrow). Blood vessels (curved arrows) are evident within mass and on its surface, but their origin and course are difficult to determine.

 


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Fig. 1B. 39-year-old woman with focal nodular hyperplasia. Portal venous phase transverse CT scan (70-sec delay) reveals blood vessels (arrows), probably veins, within mass and on its surface. Mass is nearly isoattenuating to liver.

 


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Fig. 1C. 39-year-old woman with focal nodular hyperplasia. Volume-rendered CT angiogram (20-sec delay) shows focal nodular hyperplasia (FNH) lesion supplied by anomalous artery (a a) arising from hepatic artery (HA). Lesion is drained by two hepatic vein tributaries (HV).

 


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Fig. 2A. 45-year-old woman with focal nodular hyperplasia. Early arterial phase transverse CT scan (13-sec delay) shows lesion (straight arrow) is brightly and homogeneously enhancing. Blood vessels (curved arrow) are noted on surface of mass.

 


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Fig. 2B. 45-year-old woman with focal nodular hyperplasia. Portal venous phase CT scan (60-sec delay) shows mass almost isoattenuating to liver with hypoattenuating central scar (open arrow). Large blood vessels (solid arrows) are noted.

 


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Fig. 2C. 45-year-old woman with focal nodular hyperplasia. Volume-rendered CT angiogram (13-sec delay) shows multiple branches of anomalous artery (a a) spread over lesionlike spider legs. HA = hepatic artery, FNH = focal nodular hyperplasia.

 


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Fig. 2D. 45-year-old woman with focal nodular hyperplasia. Volume-rendered CT angiogram (60-sec delay) shows that multiple draining veins (arrows) coalesce to drain into right hepatic vein (RHV) and inferior vena cava (IVC).

 


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Fig. 3. 43-year-old woman with focal nodular hyperplasia. Volume-rendered CT angiogram (20-sec delay) shows large focal nodular hyperplasia lesion (FNH) supplied by multiple branches of anomalous artery (a a) arising from hepatic artery (HA). Small lesion (FNH) is supplied by single artery.

 


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Fig. 4A. 70-year-old woman with cirrhosis and hepatocellular carcinoma. Portal venous phase transverse CT scan shows 5-cm hypoattenuating lesion in segment VIII of liver.

 


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Fig. 4B. 70-year-old woman with cirrhosis and hepatocellular carcinoma. Maximum-intensity-projection off-axial CT scan shows two enhancing vessels (straight arrows) at periphery of mass draining lesion and joining right branch of portal vein (curved arrow). On biopsy, mass was well-differentiated hepatocellular carcinoma.

 

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