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Chronic Hepatitis C Activity: Correlation with Lymphadenopathy on MR Imaging

Xiao-Ming Zhang1,2, Donald G. Mitchell1, Hongyu Shi1, George A. Holland1, Laurence Parker1, Steven K. Herrine3, Denise Pasqualin4 and Raphael Rubin4

1 Department of Radiology, Thomas Jefferson University, 1096 Main Bldg., 132 S. 10th St., Philadelphia, PA 19107.
2 Present address: Department of Radiology, Affiliated Hospital of North Sichuan Medical College, 113 Culture Rd., Nanchong, Sichuan 637000, People's Republic of China.
3 Division of Gastroenterology and Hepatology, Department of Medicine, Thomas Jefferson University, Philadelphia, PA 19107.
4 Department of Pathology, Anatomy, and Cell Biology, Thomas Jefferson University, Philadelphia, PA 19107.



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Fig. 1A. 39-year-old man with mild activity of chronic hepatitis C. Periportal lymph node measured 19 x 9 mm2. Axial gadolinium-enhanced MR images shows node (arrow).

 


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Fig. 1B. 39-year-old man with mild activity of chronic hepatitis C. Periportal lymph node measured 19 x 9 mm2. On axial fat-suppressed T2-weighted MR image, node (arrow) is isointense to spleen.

 


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Fig. 2. 51-year-old woman with moderate activity of chronic hepatitis C. Fat-suppressed T2-weighted MR image shows moderately hyperintense lymph nodes (arrows) in periportal and portocaval locations. Largest node is 26 x 12 mm2.

 


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Fig. 3. 31-year-old woman with severe activity of chronic hepatitis C. Fat-suppressed T2-weighted MR image shows multiple periportal and portocaval lymph nodes (arrows) larger than 5 mm in diameter. Largest lymph node is 24 x13 mm2. All are hyperintense relative to spleen.

 

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