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Magnetization Transfer Contrast in Rapid Three-Dimensional MR Imaging Using Segmented Radiofrequency Prepulses

Lawrence Yao1 and Dave Thomasson2

1 Department of Radiology, National Institutes of Health, Bldg. 10, Rm. 1C-640, 10 Center Dr., MSC 1182, Bethesda, MD 20892-1182.
2 Siemens Corporation, Iselin, NJ 08830.



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Fig. 1A. MR images of brain of 29-year-old healthy male volunteer. This axial three-dimensional (3D) gradient-echo MR image was obtained without prepulses (44 sections reconstructed at 2.5-mm thickness; scanning duration, 25 sec). Signal-to-noise ratio in white matter is 24.

 


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Fig. 1B. MR images of brain of 29-year-old healthy male volunteer. Axial 3D gradient-echo MR image obtained with segmented magnetization transfer prepulses at same level as A (scanning duration, 27 sec) shows magnetization transfer contrast is manifested by diminished contrast between gray and white matter. Signal-to-noise ratio in white matter is 20.

 


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Fig. 2A. MR arthrograms of shoulder in 32-year-old man with suspected gleno-humeral instability. Axial three-dimensional (3D) gradient-echo MR image obtained using fat saturation and magnetization transfer prepulses (64 sections reconstructed at 1.1-mm section thickness) shows bright injected fluid delineating anatomy of gleno-humeral capsule. Signal-to-noise ratio of injected material is 44. Magnetization transfer contrast increases contrast-to-noise ratio between injected fluid and muscle from 11.6 to 19.7

 


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Fig. 2B. MR arthrograms of shoulder in 32-year-old man with suspected gleno-humeral instability. Axial 3D gradient-echo MR image obtained using parametric magnetization transfer pulses at same level as A reveals no discernible magnetization transfer contrast in injected fluid or in fatty marrow spaces, whereas degree of magnetization transfer contrast varies in skeletal muscle, cartilage, and capsular supporting structures (color scale = 0-100%).

 

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