AJR
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Abstract Freely available
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Tomiyama, N.
Right arrow Articles by Nakamura, H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Tomiyama, N.
Right arrow Articles by Nakamura, H.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?
Hotlight (NEW!)
Right arrow
What's Hotlight?

Using the World Health Organization Classification of Thymic Epithelial Neoplasms to Describe CT Findings

Noriyuki Tomiyama1, Takeshi Johkoh2, Naoki Mihara2, Osamu Honda2, Takenori Kozuka2, Mitsuhiro Koyama2, Seiki Hamada2, Meinoshin Okumura3, Mitsunori Ohta3, Tadaaki Eimoto4, Masao Miyagawa1, Nestor L. Müller5, Junpei Ikezoe6 and Hironobu Nakamura2

1 Department of Radiology, Ehime National Hospital, 366, Yokogawara, Shigenobu, Ehime, 791-0281, Japan.
2 Department of Radiology, Osaka University Medical School, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
3 Division of General Thoracic Surgery, Department of Surgery (E-1), Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
4 Second Department of Pathology, Nagoya City University Medical School, Kawasumi, Mizuho-ku, Nagoya, 467-8601, Japan.
5 Department of Radiology, Vancouver General Hospital and University of British Columbia, 855 W. 12th Ave., Vancouver, B. C., V5Z 1M9, Canada.
6 Department of Radiology, Ehime University Medical School, Shizugawa, Shigenobu, Ehime, 791-0295, Japan.



View larger version (82K):

[in a new window]
  		Fig. 1A. —Type A tumor in 57-year-old woman. Contrast-enhanced CT scan (5-mm collimation) obtained at level of azygos arch shows homogeneous anterior mediastinum mass with smooth contours and round shape. Mass was confirmed histopathologically as noninvasive thymoma (stage I, encapsulated thymoma).

 


View larger version (142K):

[in a new window]
  		Fig. 1B. —Type A tumor in 57-year-old woman. Photomicrograph of histopathologic specimen shows spindle tumor cells (arrows) with no nuclear atypia (spindle cell type). Note small number of lymphocytes. (H and E, x200)

 


View larger version (100K):

[in a new window]
  		Fig. 2A. —Type AB tumor in 55-year-old woman. Contrast-enhanced CT scan (3-mm collimation) obtained at level of aortic arch shows oval mass in anterior mediastinum. Mass shows homogeneous enhancement with slightly higher attenuation than that of chest wall muscles.

 


View larger version (130K):

[in a new window]
  		Fig. 2B. —Type AB tumor in 55-year-old woman. Photomicrograph of histopathologic specimen shows lymphocyte-rich tumor with spindle (arrows) to oval (arrowheads) tumor epithelial cells (mixed type). Mass was confirmed histopathologically as noninvasive thymoma (stage I, encapsulated thymoma). (H and E, x200)

 


View larger version (97K):

[in a new window]
  		Fig. 3A. —Type B1 tumor in 26-year-old woman. Contrast-enhanced CT scan (7-mm collimation) obtained at right main pulmonary artery level shows mass at anterior mediastinum. Note smooth contours and oval shape of mass, which enhances heterogeneously with low attenuation.

 


View larger version (172K):

[in a new window]
  		Fig. 3B. —Type B1 tumor in 26-year-old woman. Photomicrograph of histopathologic specimen shows predominance of lymphocytes and scattered tumor epithelial cells (arrows), resembling thymic cortex (lymphocyte-rich type). Mass was confirmed histopathologically as noninvasive thymoma (stage I, encapsulated thymoma). (H and E, x200)

 


View larger version (112K):

[in a new window]
  		Fig. 4A. —Type B2 tumor in 35-year-old man. Contrast-enhanced CT scan (5-mm collimation) obtained at carinal level shows slightly heterogeneous anterior mediastinum mass with plaque shape. Mass contains punctate peripheral calcification (arrow). Invasion of pericardium was confirmed at surgery (stage III, invasive thymoma).

 


View larger version (176K):

[in a new window]
  		Fig. 4B. —Type B2 tumor in 35-year-old man. Photomicrograph of histopathologic specimen shows moderate lymphocyte infiltration and plump tumor cells (arrows) with vesicular nuclei and distinct nucleoli (cortical type). (H and E, x200)

 


View larger version (106K):

[in a new window]
  		Fig. 5A. —Type B3 tumor in 74-year-old man. Contrast-enhanced CT scan (7-mm collimation) obtained at carinal level shows lobulated contour mass at anterior mediastinum. Mass shows heterogeneous enhancement with multiple areas of decreased attenuation. Invasion of left lung and pericardium was confirmed at surgery (stage III, invasive thymoma).

 


View larger version (159K):

[in a new window]
  		Fig. 5B. —Type B3 tumor in 74-year-old man. Photomicrograph of histopathologic specimen shows sheet of tumor epithelial cells (arrows) with small number of lymphocytes and perivascular space (arrowhead) (well-differentiated thymic carcinoma). (H and E, x200)

 


View larger version (102K):

[in a new window]
  		Fig. 6A. —Type C tumor in 73-year-old man. Contrast-enhanced CT scan (3-mm collimation) obtained at carinal level shows heterogeneous anterior mediastinum mass with irregular contour. Note enlarged lymph node in right hilum (arrow). Invasion of right lung and pericardium and metastasis to right hilar node were confirmed at surgery (stage III, invasive thymoma).

 


View larger version (148K):

[in a new window]
  		Fig. 6B. —Type C tumor in 73-year-old man. Photomicrograph of histopathologic specimen shows nests of thymic carcinoma cells with atypical nuclei and with some squamous differentiation (i.e., intercellular bridges [arrows]) (thymic carcinoma). (H and E, x200)

 

Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?



HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2002 by the American Roentgen Ray Society.