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Physiologic Subperiosteal New Bone Formation: Prevalence, Distribution, and Thickness in Neonates and Infants

David S. Kwon1,2, Melissa R. Spevak1,3, Kenneth Fletcher4 and Paul K. Kleinman1,5

1 Department of Radiology and Imaging Center for Child Abuse and Neglect, UMass Memorial Health Care, 55 Lake Ave. N., Worcester, MA 01655.
2 Present address: Department of Radiology, Hallmark Health—Melrose Wakefield Campus, 585 Lebanon St., Melrose, MA 02176.
3 Present address: Department of Radiology, Johns Hopkins Hospital, 600 N. Wolfe St., Baltimore, MD 21287.
4 Department of Psychiatry, University of Massachusetts Medical School, 55 Lake Ave. N., Worcester, MA 01655.
5 Present address: Department of Radiology, Children's Hospital—Boston, 300 Longwood Ave., Boston, MA 02115.



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Fig. 1. Method of measuring subperiosteal new bone formation is illustrated. Radiograph (left side of figure) of 3-month-old infant shows subperiosteal new bone formation along medial aspect of right tibia. Right side of figure is magnified view with superimposed ruler simulating ocular magnification system used in study. subperiosteal new bone formation in this infant measures 1.8 mm, a common measurement finding. Div = division.

 


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Fig. 2. Graph shows prevalence of subperiosteal new bone formation by age and multiplicity of affected anatomic sites. {blacksquare} = total number of infants in age group, {square} = number of infants in age group with subperiosteal new bone formation, [UNK] = number of infants with subperiosteal new bone formation in multiple sites.

 


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Fig. 3. Graph shows distribution of subperiosteal new bone formation by bone involved. {blacksquare} = total number of bones with subperiosteal new bone formation at designated site, {square} = number of infants with bilateral involvement by subperiosteal new bone formation in specified bone, [UNK] = number of infants with unilateral involvement by subperiosteal new bone formation in specified bone.

 

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