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Preoperative Assessment of Breast Cancer: Sonography Versus MR Imaging

Alexander Hlawatsch1, Andrea Teifke1, Marcus Schmidt2 and Manfred Thelen1

1 Department of Radiology, Johannes Gutenberg University Hospital, Langenbeckstr. 1, 55131 Mainz, Germany.
2 Department of Gynecology, Johannes Gutenberg University Hospital, 55131 Mainz, Germany.



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Fig. 1A. 77-year-old woman with diffuse ductal carcinoma of right breast and suspected bilateral cancer. Craniocaudal mammogram of left breast shows round mass (arrows) with smooth borders that appears to be benign.

 


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Fig. 1B. 77-year-old woman with diffuse ductal carcinoma of right breast and suspected bilateral cancer. Sonogram of lesion in left breast reveals hypoechoic lesion (large arrow) with solid internal structure (small arrow), suggestive of papilloma or intracystic carcinoma that requires biopsy.

 


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Fig. 1C. 77-year-old woman with diffuse ductal carcinoma of right breast and suspected bilateral cancer. Unenhanced T1-weighted MR image depicts lesion (arrow) in left breast.

 


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Fig. 1D. 77-year-old woman with diffuse ductal carcinoma of right breast and suspected bilateral cancer. Contrast-enhanced T1-weighted MR image depicts lesion (arrow) in left breast.

 


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Fig. 1E. 77-year-old woman with diffuse ductal carcinoma of right breast and suspected bilateral cancer. Digital subtraction MR image (corresponding to C and D) shows strongly enhancing round lesion (arrow), falsely suggesting carcinoma. Final histologic diagnosis was papilloma.

 


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Fig. 1F. 77-year-old woman with diffuse ductal carcinoma of right breast and suspected bilateral cancer. Unenhanced T1-weighted MR image shows right breast.

 


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Fig. 1G. 77-year-old woman with diffuse ductal carcinoma of right breast and suspected bilateral cancer. Contrast-enhanced T1-weighted MR image shows right breast.

 


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Fig. 1H. 77-year-old woman with diffuse ductal carcinoma of right breast and suspected bilateral cancer. Digital subtraction MR image (corresponding to F and G) reveals diffuse, growing tumor (arrows) with relatively weak enhancement.

 


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Fig. 2A. 44-year-old woman with multifocal mixed tubular—lobular carcinoma of right breast. Recommendation for mastectomy was made after sonography and was confirmed after MR imaging. Histology found disseminated small invasive foci within extensive lobular carcinoma in situ. Bilateral mediolateral mammogram shows asymmetric inhomogeneous tissue with architectural distortion (arrows) in right breast, suggesting diffuse disease.

 


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Fig. 2B. 44-year-old woman with multifocal mixed tubular—lobular carcinoma of right breast. Recommendation for mastectomy was made after sonography and was confirmed after MR imaging. Histology found disseminated small invasive foci within extensive lobular carcinoma in situ. Sonogram of right breast shows suspicious 5.9-mm hypoechoic lesion (arrow) with irregular borders. Four identical lesions were identified within range of 4 cm. Because of disseminated tumor in relatively small breast, mastectomy was recommended.

 


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Fig. 2C. 44-year-old woman with multifocal mixed tubular—lobular carcinoma of right breast. Recommendation for mastectomy was confirmed. Histology found disseminated small invasive foci within extensive lobular carcinoma in situ. Unenhanced T1-weighted MR image depicts right breast.

 


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Fig. 2D. 44-year-old woman with multifocal mixed tubular—lobular carcinoma of right breast. Recommendation for mastectomy was confirmed. Histology found disseminated small invasive foci within extensive lobular carcinoma in situ. Contrast-enhanced T1-weighted MR image of right breast was obtained at same level as C.

 


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Fig. 2E. 44-year-old woman with multifocal mixed tubular—lobular carcinoma of right breast. Recommendation for mastectomy was confirmed. Histology found disseminated small invasive foci within extensive lobular carcinoma in situ. Digital subtraction MR image of right breast (corresponding to C and D) shows disseminated lesions (arrows).

 


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Fig. 2F. 44-year-old woman with multifocal mixed tubular—lobular carcinoma of right breast. Recommendation for mastectomy was confirmed. Histology found disseminated small invasive foci within extensive lobular carcinoma in situ. Unenhanced T1-weighted MR image of right breast was obtained at level subsequent to level of C—E.

 


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Fig. 2G. 44-year-old woman with multifocal mixed tubular—lobular carcinoma of right breast. Recommendation for mastectomy was confirmed. Histology found disseminated small invasive foci within extensive lobular carcinoma in situ. Contrast-enhanced T1-weighted MR image of right breast was obtained at same level as F.

 


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Fig. 2H. 44-year-old woman with multifocal mixed tubular—lobular carcinoma of right breast. Recommendation for mastectomy was confirmed. Histology found disseminated small invasive foci within extensive lobular carcinoma in situ. Digital subtraction MR image of right breast (corresponding to F and G) shows disseminated lesions (arrows).

 


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Fig. 2I. 44-year-old woman with multifocal mixed tubular—lobular carcinoma of right breast. Recommendation for mastectomy was confirmed. Histology found disseminated small invasive foci within extensive lobular carcinoma in situ. Unenhanced T1-weighted MR image of right breast obtained at level subsequent to level of F—H shows full extent of tumor.

 


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Fig. 2J. 44-year-old woman with multifocal mixed tubular—lobular carcinoma of right breast. Recommendation for mastectomy was confirmed. Histology found disseminated small invasive foci within extensive lobular carcinoma in situ. Contrast-enhanced T1-weighted MR image of right breast was obtained at same level as I.

 


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Fig. 2K. 44-year-old woman with multifocal mixed tubular—lobular carcinoma of right breast. Recommendation for mastectomy was confirmed. Histology found disseminated small invasive foci within extensive lobular carcinoma in situ. Digital subtraction MR image of right breast (corresponding to I and J) reveals multiple disseminated foci (arrow).

 

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