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Multidetector CT of High-Risk Patients with Occult Gastrointestinal Stromal Tumors

Toshirou Nishida1, Seishi Kumano2, Takashi Sugiura2, Hirofumi Ikushima1, Kazuhiro Nishikawa1, Toshinori Ito1 and Hikaru Matsuda1

1 Department of Surgery, E1, Osaka University Graduate School of Medicine, Yamada-oka 2-2, Suita 565-0871, Japan.
2 Department of Radiology, Osaka University Graduate School of Medicine, Suita 565-0871, Japan.



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  		Fig. 1. —Bar graph shows relationship between tumor size and presence of macroscopic tumor necrosis. Gray and black bars indicate number of patients with and without macroscopic necrosis, respectively. Frequency of tumors with necrosis rises with increases in tumor size (p < 0.0001).

 


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  		Fig. 2A. —36-year-old man with germline c-kit mutation (patient 5). Endoscopic sonogram shows submucosal tumors in cardia.

 


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  		Fig. 2B. —36-year-old man with germline c-kit mutation (patient 5). Endoscopic sonogram also shows submucosal tumors in gastric corpus.

 


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  		Fig. 2C. —36-year-old man with germline c-kit mutation (patient 5). CT scan shows slightly enhanced submucosal tumors in cardia.

 


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  		Fig. 2D. —36-year-old man with germline c-kit mutation (patient 5). CT scans also show submucosal tumors in gastric corpus as slightly enhanced intramural tumors.

 


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  		Fig. 2E. —36-year-old man with germline c-kit mutation (patient 5). CT scans also show submucosal tumors in gastric corpus as slightly enhanced intramural tumors.

 


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  		Fig. 3. —70-year-old woman with germline c-kit mutation (patient 2). CT scan shows submucosal tumors in cardia, which were slightly enhanced by IV infusion of contrast medium.

 


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  		Fig. 4. —68-year-old woman with germline c-kit mutation (patient 3). CT scan shows jejunal submucosal tumor growing into intestinal lumen and enhanced by IV infusion of contrast medium.

 

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