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MR Venography Using an Intravascular Contrast Agent: Results from a Multicenter Phase 2 Study of Dosage

Elna-Marie Larsson1, Paul Sundén1, Carl-Gustav Olsson2, Jörg Debatin3, Andre J. Duerinckx4, Richard Baum5, Dietbert Hahn6 and Franz Ebner7

1 Department of Neuroradiology, Center for Medical Imaging and Physiology, Lund University Hospital, SE-221 85, Lund, Sweden.
2 Department of Internal Medicine, Lund University Hospital, SE-221 85, Lund, Sweden.
3 Department of Diagnostic Radiology, University Hospital Essen, Hufelandstr. 55, DE-45122 Essen, Germany.
4 Radiology Service, VA North Texas Healthcare System, 4500 S. Lancaster Rd., Dallas, TX 75216.
5 Department of Radiology, The Brigham and Women's Hospital, 75 Francis St., Boston, MA 02115.
6 Institut für Röntgendiagnostik, Universität Würzburg, DE-97080 Würzburg, Germany.
7 MR-Institute, University Hospital Graz, Auenbruggerplatz 9, AT-8036 GRAZ, Austria.



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  		Fig. 1A. —Contrast-enhanced MR venography in 78-year-old man with thrombosis of all deep veins of lower leg, popliteal vein, and superficial femoral vein on left side that was documented on radiographic venography. Coronal maximum-intensity-projection image of lower abdominal and pelvic vessels including internal iliac veins reveals no thrombosis.

 


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  		Fig. 1B. —Contrast-enhanced MR venography in 78-year-old man with thrombosis of all deep veins of lower leg, popliteal vein, and superficial femoral vein on left side that was documented on radiographic venography. Oblique coronal maximum-intensity-projection image of thighs shows no contrast filling of left popliteal vein and superficial femoral vein. Upper portion of thrombus (arrow) is seen as defect in superficial femoral vein. Note visualization of deep femoral veins.

 


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  		Fig. 1C. —Contrast-enhanced MR venography in 78-year-old man with thrombosis of all deep veins of lower leg, popliteal vein, and superficial femoral vein on left side that was documented on radiographic venography. Transverse multiplanar reconstruction image shows thrombus (arrow) in left superficial femoral vein.

 


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  		Fig. 2. —32-year-old man with thrombosis of right fibular and anterior tibial veins that was documented on radiographic venography. Transverse multiplanar reconstruction of contrast-enhanced MR venogram of calves shows thrombus (arrow) in right fibular vein.

 

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