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Hilar Biliary Obstruction: Preliminary Results with Levovist-Enhanced Sonography

Korosh Khalili1, Ur Metser and Stephanie R. Wilson

1 All authors: Department of Medical Imaging, Toronto General Hospital, University Health Network, 200 Elizabeth St., Toronto, Ontario, Canada M5G 2C4.



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Fig. 1A. Malignant biliary obstruction in 68-year-old man with invasive cholangiocarcinoma. Transverse unenhanced sonogram shows segmental dilated ducts in right lobe that terminate blindly in region of porta hepatis. No mass is visualized.

 


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Fig. 1B. Malignant biliary obstruction in 68-year-old man with invasive cholangiocarcinoma. Transverse postvascular contrast-enhanced sonogram shows large invasive tumor with intraductal and periductal extension.

 


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Fig. 2A. Malignant hilar obstruction from cholangiocarcinoma with metastatic liver nodules in 77-year-old man. Transverse unenhanced sonogram shows mass in left lobe and dilated ducts (arrowheads) in right lobe of liver.

 


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Fig. 2B. Malignant hilar obstruction from cholangiocarcinoma with metastatic liver nodules in 77-year-old man. Transverse contrast-enhanced sonogram clearly shows larger mass with increased conspicuity and better defined borders. Also visible is small isolated metastasis in liver (arrow) that was seen only on enhanced imaging.

 


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Fig. 2C. Malignant hilar obstruction from cholangiocarcinoma with metastatic liver nodules in 77-year-old man. Confirmatory CT scan shows large primary tumor and liver metastasis (arrow).

 


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Fig. 3A. Malignant hilar obstruction from invasive gallbladder carcinoma with extensive intraductal tumor extension in 83-year-old woman. Transverse unenhanced sonogram shows dilated intrahepatic biliary ducts and visible intraductal tumor (arrowheads).

 


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Fig. 3B. Malignant hilar obstruction from invasive gallbladder carcinoma with extensive intraductal tumor extension in 83-year-old woman. Transverse contrast-enhanced sonogram improves conspicuity of duct walls and intraductal tumor (arrowheads). No invasive tumor is seen at this level.

 


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Fig. 3C. Malignant hilar obstruction from invasive gallbladder carcinoma with extensive intraductal tumor extension in 83-year-old woman. CT scan obtained at same level does not depict intraductal tumor. Invasive obstructing mass (not shown) at porta hepatis was seen on another CT scan and on postvascular phase contrast-enhanced sonogram.

 


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Fig. 4A. Malignant hilar obstruction from cholangiocarcinoma in 42-year-old man with large intraductal tumor. Transverse unenhanced sonogram of left lobe of liver shows poorly defined mass (arrowheads).

 


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Fig. 4B. Malignant hilar obstruction from cholangiocarcinoma in 42-year-old man with large intraductal tumor. Transverse contrast-enhanced sonogram shows abnormality to be tumor-filled left hepatic duct (arrowheads). No parenchymal invasion is seen.

 


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Fig. 4C. Malignant hilar obstruction from cholangiocarcinoma in 42-year-old man with large intraductal tumor. Confirmatory CT scan shows same findings as contrast-enhanced sonogram (B).

 


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Fig. 5A. Benign biliary obstruction due to primary sclerosing cholangitis in 42-year-old woman with periductal thickening. Transverse unenhanced sonogram obtained through porta hepatis reveals periportal region with vague slightly hypoechoic areas (arrowheads).

 


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Fig. 5B. Benign biliary obstruction due to primary sclerosing cholangitis in 42-year-old woman with periductal thickening. Transverse contrast-enhanced sonogram shows extensive periductal soft-tissue thickening (arrowheads) around central biliary tree.

 


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Fig. 5C. Benign biliary obstruction due to primary sclerosing cholangitis in 42-year-old woman with periductal thickening. Confirmatory contrast-enhanced CT scan shows regions (arrowheads) as hypoattenuating relative to enhancing liver.

 


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Fig. 6A. Benign inflammatory masses mimicking cholangiocarcinoma on contrast-enhanced sonography and MR imaging in 63-year-old man 6 years after left liver resection for cholangiocarcinoma. Transverse sonogram shows dilated segmental bile duct (arrow) at resection margin in liver ventral relative to right portal vein.

 


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Fig. 6B. Benign inflammatory masses mimicking cholangiocarcinoma on contrast-enhanced sonography and MR imaging in 63-year-old man 6 years after left liver resection for cholangiocarcinoma. Transverse postvascular contrast-enhanced sonogram obtained in same plane as A shows multiple nonenhancing nodules (arrowhead) in periductal region (arrow).

 


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Fig. 6C. Benign inflammatory masses mimicking cholangiocarcinoma on contrast-enhanced sonography and MR imaging in 63-year-old man 6 years after left liver resection for cholangiocarcinoma. Confirmatory gadolinium-enhanced T1-weighted MR image shows same dilated segmental bile duct (arrow) surrounded by enhancing soft-tissue nodules (arrowhead). Both MR image and sonogram were interpreted as showing recurrent cholangiocarcinoma.

 

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