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Chronic Cystic Lung Disease: Diagnostic Accuracy of High-Resolution CT in 92 Patients

Mitsuhiro Koyama1, Takeshi Johkoh1, Osamu Honda1, Mitsuko Tsubamoto1, Takenori Kozuka1, Noriyuki Tomiyama1, Seiki Hamada1, Hironobu Nakamura1, Masanori Akira2, Kazuya Ichikado3, Kiminori Fujimoto4, Toru Rikimaru5, Ukihide Tateishi6 and Nestor L. Müller7

1 Department of Radiology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
2 Department of Radiology, National Kinki Chuo Hospital for Chest Disease, 1180 Nagasone-cho, Sakai, Osaka, 591-8025, Japan.
3 First Department of Internal Medicine, Kumamoto University School of Medicine, 1-1-1 Honjo, Kumamoto, 860-0811, Japan.
4 Department of Radiology, Kurume University School of Medicine, 67 Asahi-machi, Kurume, 830-0011, Japan.
5 First Department of Internal Medicine, Kurume University School of Medicine, Kurume, 830-0011, Japan.
6 Department of Radiology, Hokkaido University School of Medicine, North-15, West-7, Kita-Ku, Sapporo, 060-8638, Japan.
7 Department of Radiology, University of British Columbia and Vancouver Hospital and Health Sciences Center, 855 W. 12th Ave., Vancouver, B. C. V5Z 1M9, Canada.



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Fig. 1. Usual interstitial pneumonia in 69-year-old man. High-resolution (1-mm-collimation) CT scan obtained at level of right inferior pulmonary vein shows extensive areas of ground-glass attenuation with honeycombing (arrowheads). Cystic air spaces are clustered and share walls. Note traction bronchiectasis (arrows).

 


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Fig. 2. Desquamative interstitial pneumonia in 57-year-old man. High-resolution (1-mm-collimation) CT scan obtained at level of right inferior pulmonary vein reveals areas of ground-glass attenuation (arrowheads) involving mainly subpleural lung regions. Note localized areas of low attenuation near center of secondary lobules (arrows).

 


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Fig. 3. Lymphocytic interstitial pneumonia in 49-year-old woman. High-resolution (1-mm-collimation) CT scan obtained at level of tracheal carina shows several thin-walled cystic air spaces (large arrows) and thickened bronchovascular bundles (small arrows). Note poorly defined centrilobular nodules, areas of ground-glass attenuation, and thickening of interlobular septa (arrowheads).

 


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Fig. 4. Langerhans cell histiocytosis in 24-year-old woman. High-resolution (1-mm-collimation) CT scan obtained at level of tracheal carina reveals numerous thin- and thick-walled cysts (arrows) in right upper lobe. Some cysts are very irregular in shape. Note several nodules (arrowheads).

 


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Fig. 5. Lymphangioleiomyomatosis in 46-year-old woman. High-resolution (1-mm-collimation) CT scan obtained at level of tracheal carina shows innumerable contiguous cysts throughout lung parenchyma. Cysts are variable in appearance, having differing shapes and sizes and various degrees of wall thickness.

 


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Fig. 6. Emphysema in 75-year-old man. High-resolution (1-mm-collimation) CT scan obtained at level of tracheal carina reveals localized areas of low attenuation near center of secondary lobules. No discrete cyst walls are seen.

 

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