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Nondysplastic Nodules That Are Hyperintense on T1-Weighted Gradient-Echo MR Imaging: Frequency in Cirrhotic Patients Undergoing Transplantation

Glenn A. Krinsky1 and Gary Israel

1 Both authors: Department of Radiology, NYU Medical Center, 530 First Ave., Basement Schwartz Bldg., New York, NY 10016.



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Fig. 1A. 23-year-old woman with autoimmune cirrhosis. Transverse in-phase T1-weighted gradient-echo MR image (TR/TE, 175/4.4; flip angle, 90°) also shows two hyperintense nodules (arrows).

 


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Fig. 1B. 23-year-old woman with autoimmune cirrhosis. Transverse opposed-phase T1-weighted gradient-echo MR image (175/2.2; flip angle, 90°) shows two hyperintense nodules (arrows). Note that two nodules showed no signal loss compared with appearance in A.

 


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Fig. 1C. 23-year-old woman with autoimmune cirrhosis. Transverse turbo STIR image (5200/76; inversion time, 165 msec) shows nodules (arrows) as hypointense compared with background of cirrhotic liver in right lobe and as isointense relative to caudate lobe.

 


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Fig. 1D. 23-year-old woman with autoimmune cirrhosis. Transverse in-phase T1-weighted gradient-echo MR image (225/4.4; flip angle, 90°) of ex vivo liver obtained 11 days after AC shows nodule (arrow) in lateral segment as hyperintense and larger than cirrhotic nodules in background.

 


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Fig. 1E. 23-year-old woman with autoimmune cirrhosis. Transverse opposed-phase T1-weighted gradient-echo MR image (225/2.2; flip angle, 90°) of ex vivo liver shows no signal loss in nodule (arrow) is visible when compared with D.

 


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Fig. 2A. 42-year-old man with cirrhosis due to hepatitis B and ethanol abuse. Transverse in-phase T1-weighted gradient-echo MR image (TR/TE, 175/4.4; flip angle, 80°) shows 2.5-cm hyperintense nodule (arrow).

 


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Fig. 2B. 42-year-old man with cirrhosis due to hepatitis B and ethanol abuse. Transverse opposed-phase T1-weighted gradient-echo MR image (175/2.2; flip angle, 80°) shows nodule (arrow) exhibits no signal loss compared with A.

 


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Fig. 2C. 42-year-old man with cirrhosis due to hepatitis B and ethanol abuse. Photomicrograph of coronal section (perpendicular to A and B) from liver explanted 25 days after MR imaging shows large regenerative nodules with cholestatic changes but no dysplastic nodules.

 

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