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Sonographic Detection and Sonographically Guided Biopsy of Breast Microcalcifications

¹ All authors: Department of Radiology, Breast Imaging Division, Duke University Medical Center, P.O. Box 3808, Durham, NC 27710.

View larger version (87K): [in a new window]   Fig. 1A. —75-year-old woman with invasive ductal carcinoma in right breast. Spot magnification mammogram shows linear and branching microcalcifications highly suggestive of malignancy.

View larger version (132K): [in a new window]   Fig. 1B. —75-year-old woman with invasive ductal carcinoma in right breast. Sonogram of region of microcalcifications shows enlarged hypoechoic duct (arrowheads) with internal echogenic microcalcifications (arrows). On sonographically guided core biopsy (not shown), microcalcifications in duct were targeted.

View larger version (114K): [in a new window]   Fig. 1C. —75-year-old woman with invasive ductal carcinoma in right breast. Specimen radiograph from core biopsy shows microcalcifications (arrows) in specimens.

View larger version (126K): [in a new window]   Fig. 2A. —73-year-old woman with invasive ductal carcinoma in right breast. Spot magnification mammogram shows pleomorphic microcalcifications suspicious for malignancy.

View larger version (89K): [in a new window]   Fig. 2B. —73-year-old woman with invasive ductal carcinoma in right breast. Sonogram of region of microcalcifications shows lobulated ill-defined mass (arrowheads) with associated microcalcifications (arrows).

View larger version (96K): [in a new window]   Fig. 2C. —73-year-old woman with invasive ductal carcinoma in right breast. Sonogram obtained during core needle biopsy shows needle (arrows) traversing mass (arrowheads).

View larger version (134K): [in a new window]   Fig. 2D. —73-year-old woman with invasive ductal carcinoma in right breast. Specimen radiograph from core biopsy shows microcalcification (arrow) in specimen.

View larger version (109K): [in a new window]   Fig. 3A. —41-year-old woman with metastatic adenocarcinoma in right axillary lymph nodes and ductal carcinoma in situ with necrosis in right breast. Sonogram obtained before biopsy of region of mammographic microcalcifications shows ill-defined hypoechoic mass (arrowheads) with microcalcifications (arrows) located superficially.

View larger version (120K): [in a new window]   Fig. 3B. —41-year-old woman with metastatic adenocarcinoma in right axillary lymph nodes and ductal carcinoma in situ with necrosis in right breast. Sonogram obtained during core needle biopsy shows needle (arrowheads) transversing superficial portion of mass, targeting microcalcifications (arrow). Microcalcifications were not seen on specimen radiograph (not shown), and marker clip was deployed with sonographic guidance.

View larger version (137K): [in a new window]   Fig. 3C. —41-year-old woman with metastatic adenocarcinoma in right axillary lymph nodes and ductal carcinoma in situ with necrosis in right breast. Magnification craniocaudal mammogram obtained after biopsy shows residual pleomorphic microcalcifications (arrowheads) with adjacent marker clip (arrow) in close proximity to microcalcifications.

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