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Widespread Ground-Glass Opacity of the Lung in Consecutive Patients Undergoing CT: Does Lobular Distribution Assist Diagnosis?

Rosita M. Shah1 and Wallace Miller, Jr.2

1 Department of Radiology, Thomas Jefferson University Hospital, 111 S. 11th St., 3390 Gibbon, Philadelphia, PA 19107.
2 Department of Radiology, University of Pennsylvania Hospital, Philadelphia, PA 19104.



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  		Fig. 1. —45-year-old HIV-positive woman with pneumocystis pneumonia. High-resolution CT scan shows random distribution of ground-glass opacity.

 


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  		Fig. 2. —62-year-old man 1 month after renal transplantation with cytomegalovirus pneumonitis. Targeted high-resolution CT scan of right lung shows ground-glass opacity with prominent centrilobular features.

 


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  		Fig. 3. —68-year-old man with nonspecific interstitial pneumonitis. High-resolution CT scan at lung bases reveals focal areas of ground-glass opacity with random distribution.

 


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  		Fig. 4. —41-year-old woman with desquamative interstitial pneumonitis. High-resolution CT scan of right upper lobe reveals centrilobular distribution of ground-glass opacity.

 


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  		Fig. 5. —23-year-old woman after bone marrow transplantation for acute lymphocytic leukemia with acute alveolar hemorrhage. Targeted high-resolution CT scan of right upper lobe reveals lobular distribution of ground-glass opacity.

 


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  		Fig. 6. —57-year-old man with bronchogenic carcinoma with acute radiation pneumonitis and histologic evidence of diffuse alveolar damage. High-resolution CT scan reveals widespread, randomly distributed ground-glass opacity. Sharp lateral margin in right lung corresponds to known radiation field.

 


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  		Fig. 7. —72-year-old woman with colon cancer after treatment with CPT-11. High-resolution CT scan reveals widespread ground-glass opacity with lobular distribution.

 

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