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Multidetector CT of the Liver and Hepatic Neoplasms: Effect of Multiphasic Imaging on Tumor Conspicuity and Vascular Enhancement

Isaac R. Francis1, Richard H. Cohan1, Nancy J. McNulty1, Joel F. Platt1, Melvyn Korobkin1, Achamyeleh Gebremariam2 and Kartik Ragupathi2

1 Department of Radiology, University of Michigan Hospitals, 1500 E. Medical Center Dr., Ann Arbor, MI 48109-0030.
2 Department of Internal Medicine, University of Michigan Hospitals, Ann Arbor, MI 48109.



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  		Fig. 1A. —52-year-old man with metastases from colon carcinoma. Enhanced multiphasic axial CT scan obtained in arterial phase shows no portal vein enhancement.

 


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  		Fig. 1B. —52-year-old man with metastases from colon carcinoma. Enhanced multiphasic axial CT scan obtained in late arterial phase shows some enhancement in portal vein (arrow). Arrowhead shows metastasis.

 


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  		Fig. 1C. —52-year-old man with metastases from colon carcinoma. Enhanced multiphasic axial CT scan obtained in portal venous phase shows most marked enhancement of portal vein (arrow) in comparison with A and B.

 


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  		Fig. 2A. —57-year-old man with hepatocellular carcinoma. Enhanced multiphasic axial CT scans obtained in early arterial phase (A) and late arterial phase (B) show hypervascular hepatocellular carcinoma (arrow, B) poorly in early arterial phase (A), but best in late arterial phase (B).

 


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  		Fig. 2B. —57-year-old man with hepatocellular carcinoma. Enhanced multiphasic axial CT scans obtained in early arterial phase (A) and late arterial phase (B) show hypervascular hepatocellular carcinoma (arrow, B) poorly in early arterial phase (A), but best in late arterial phase (B).

 


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  		Fig. 2C. —57-year-old man with hepatocellular carcinoma. Enhanced multiphasic axial CT scan obtained in portal venous phase shows that hypervascular hepatocellular carcinoma is now hypodense to liver.

 


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  		Fig. 3A. —76-year-old woman with hypervascular metastases from primary extrahepatic neuroendocrine tumor. Enhanced multiphasic axial CT scan obtained in early arterial phase shows small hypervascular metastases poorly, except for largest one in left lobe (arrow).

 


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  		Fig. 3B. —76-year-old woman with hypervascular metastases from primary extrahepatic neuroendocrine tumor. Enhanced multiphasic axial CT scan obtained in late arterial phase clearly shows large hypervascular (arrow) and smaller hypervascular metastases (arrowheads).

 


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  		Fig. 3C. —76-year-old woman with hypervascular metastases from primary extrahepatic neuroendocrine tumor. Enhanced multiphasic axial CT scan obtained in portal venous phase shows large hypervascular metastasis (arrow); other metastases are isodense to liver.

 


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  		Fig. 4A. —76-year-old woman with metastases from colon carcinoma. Enhanced multiphasic axial CT scan obtained in early arterial phase shows hypovascular metastasis (arrow) poorly.

 


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  		Fig. 4B. —76-year-old woman with metastases from colon carcinoma. Enhanced multiphasic axial CT scans obtained in late arterial phase (B) and portal venous phase (C) show hypovascular metastasis (arrows) less clearly in arterial phase (B) than in portal venous phase (C).

 


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  		Fig. 4C. —76-year-old woman with metastases from colon carcinoma. Enhanced multiphasic axial CT scans obtained in late arterial phase (B) and portal venous phase (C) show hypovascular metastasis (arrows) less clearly in arterial phase (B) than in portal venous phase (C).

 

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