Time-Resolved Three-Dimensional MR Imaging of Gastric Emptying Modified by IV Administration of Erythromycin
Thomas C. Lauenstein1,
Florian M. Vogt1,
Christoph U. Herborn1,
Armin DeGreiff2,
Jörg F. Debatin1 and
Gerald Holtmann3
1 Department of Diagnostic Radiology, University Hospital Essen, Hufelandstr.
55, D-45122 Essen, Germany.
2 Department of Neurology, University Hospital Essen, D-45122 Essen,
Germany.
3 Department of Gastroenterology and Hepatology, University Hospital Essen,
D-45122 Essen, Germany.
View larger version (85K):
[in a new window]
|
Fig. 1A. —Images obtained in healthy 34-year-old male volunteer. High
contrast between bright gastric lumen, which contains paramagnetic contrast
material, and dark surrounding tissue allows rate of gastric emptying to be
calculated. Three dimensional MR imaging data sets provides easy delineation
of anatomic structures on images obtained in coronal (A), reconstructed
sagittal (B), and axial (C) planes and on
maximum-intensity-projection re-constructions (D).
|
|
View larger version (106K):
[in a new window]
|
Fig. 1B. —Images obtained in healthy 34-year-old male volunteer. High
contrast between bright gastric lumen, which contains paramagnetic contrast
material, and dark surrounding tissue allows rate of gastric emptying to be
calculated. Three dimensional MR imaging data sets provides easy delineation
of anatomic structures on images obtained in coronal (A), reconstructed
sagittal (B), and axial (C) planes and on
maximum-intensity-projection re-constructions (D).
|
|
View larger version (93K):
[in a new window]
|
Fig. 1C. —Images obtained in healthy 34-year-old male volunteer. High
contrast between bright gastric lumen, which contains paramagnetic contrast
material, and dark surrounding tissue allows rate of gastric emptying to be
calculated. Three dimensional MR imaging data sets provides easy delineation
of anatomic structures on images obtained in coronal (A), reconstructed
sagittal (B), and axial (C) planes and on
maximum-intensity-projection re-constructions (D).
|
|
View larger version (102K):
[in a new window]
|
Fig. 1D. —Images obtained in healthy 34-year-old male volunteer. High
contrast between bright gastric lumen, which contains paramagnetic contrast
material, and dark surrounding tissue allows rate of gastric emptying to be
calculated. Three dimensional MR imaging data sets provides easy delineation
of anatomic structures on images obtained in coronal (A), reconstructed
sagittal (B), and axial (C) planes and on
maximum-intensity-projection re-constructions (D).
|
|
View larger version (141K):
[in a new window]
|
Fig. 2. —Image obtained in healthy 30-year-old male volunteer shows
segmentation of stomach using three-dimensional (3D) region-growing algorithm
from user-selected point in hyperintense gadolinium-containing gastric area.
Threshold and blurring factor for edge detection are adjustable in 3D MR
imaging. Note gastric contents (asterisk).
|
|
View larger version (111K):
[in a new window]
|
Fig. 3A. —MR images from three-dimensional data sets obtained in
healthy 30-year-old male volunteer who had not received IV erythromycin.
Coronal source images obtained at initialization (0 min, A) and at end
(25 min, B) of examination depict gastric emptying and subsequent
small-bowel filling.
|
|
View larger version (122K):
[in a new window]
|
Fig. 3B. —MR images from three-dimensional data sets obtained in
healthy 30-year-old male volunteer who had not received IV erythromycin.
Coronal source images obtained at initialization (0 min, A) and at end
(25 min, B) of examination depict gastric emptying and subsequent
small-bowel filling.
|
|
View larger version (101K):
[in a new window]
|
Fig. 5A. —Contrast-enhanced coronal source images of three-dimensional
MR imaging data sets of gastric emptying obtained in 34-year-old male
volunteer who had not received erythromycin. MR image was obtained immediately
after injection of contrast material.
|
|
View larger version (118K):
[in a new window]
|
Fig. 5B. —Contrast-enhanced coronal source images of three-dimensional
MR imaging data sets of gastric emptying obtained in 34-year-old male
volunteer who had not received erythromycin. MR image obtained 25 min after
injection of contrast material shows considerable small-bowel filling.
|
|
View larger version (109K):
[in a new window]
|
Fig. 6A. —Contrast-enhanced coronal source images of three-dimensional
MR imaging data sets of gastric emptying in 44-year-old man with functional
dyspepsia obtained before he received erythromycin. MR image was obtained
immediately after injection of contrast material.
|
|
View larger version (116K):
[in a new window]
|
Fig. 6B. —Contrast-enhanced coronal source images of three-dimensional
MR imaging data sets of gastric emptying in 44-year-old man with functional
dyspepsia obtained before he received erythromycin. MR image obtained 25 min
after injection of contrast material shows that rate of gastric emptying in
patient is significantly slower than rate observed in healthy volunteer in
Figures 5A,
5B.
|
|
View larger version (123K):
[in a new window]
|
Fig. 7. —Maximum-intensity-projection image from three-dimensional MR
imaging data set obtained in 57-year-old woman with functional dyspepsia.
Patient's rates of gastric emptying were not significantly different from
reference values in volunteers, but esophageal reflux (arrow) was
detected.
|
|
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
Copyright © 2003 by the American Roentgen Ray Society.
) and without (
) IV
administration of erythromycin. Range is indicated by [UNK].