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Catheter-Directed Thrombolytic Therapy in Peripheral Artery Occlusions: Combining Reteplase and Abciximab

Peter Drescher1,2, James McGuckin3, William S. Rilling1 and Martin R. Crain1,2

1 Department of Radiology, Medical College of Wisconsin, 9200 W. Wisconsin Ave., Milwaukee, WI 53226.
2 Great Lakes Radiologists, 2560 Norman Ct., Brookfield, WI 53045.
3 Department of Radiologists, Our Lady of Lourdes Medical Center, 1600 Haddon Ave., Camden, NJ 08103.



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  		Fig. 1A. —Magnified digital subtraction angiograms of left forearm and wrist of 63-year-old woman. Image reveals occlusion of ulnar and radial arteries, filling of incomplete palmar arch through collaterals, and decreased perfusion of metacarpal and digital arteries. These findings are almost the same as those seen on angiogram obtained 6 months earlier (not shown).

 


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  		Fig. 1B. —Magnified digital subtraction angiograms of left forearm and wrist of 63-year-old woman. Image after intraarterial catheter-directed thrombolysis with 10 U of reteplase (20 hr) and IV infusion of abciximab (12 hr) shows reperfusion of ulnar artery with significant improved filling of palmar arch and of metacarpal and digital arteries.

 

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