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Diagnostic Accuracy of Phase-Inversion Tissue Harmonic Imaging Versus Fundamental B-Mode Sonography in the Evaluation of Focal Lesions of the Kidney

Thorsten Schmidt1, Christian Hohl1, Patrick Haage1, Marcus Blaum1, Dagmar Honnef1, Claudia Weiß2, Gundula Staatz1 and R. W. Günther1

1 Department of Diagnostic Radiology, RWTH Aachen University Hospital, Pauwelsstr. 30, Aachen D 52057, Germany.
2 Institute for Biometrics, RWTH Aachen University Hospital, Aachen D 52057, Germany.



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Fig. 1A. Small uncomplicated cyst of right kidney (7 mm in diameter) in 76-year-old man. Fundamental B-mode sonogram shows intraluminal reverberation artifacts. Lesion borders are not sharply demarcated, and through-transmission with posterior echo enhancement is subtle.

 


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Fig. 1B. Small uncomplicated cyst of right kidney (7 mm in diameter) in 76-year-old man. Phase-inversion tissue harmonic image shows sharp and thin cyst walls and echo-free internal structure, which is characteristic of uncomplicated cysts. Posterior acoustic enhancement is more pronounced.

 


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Fig. 2A. Complicated cystic lesion with multiple partly thickened septations in 64-year-old woman. Contrast-enhanced CT scan (not shown) revealed complicated cystic lesion with solid septal portions. Lesion was not removed, and six monthly follow-up CT scans (not shown) did not show any changes over period of 1 year. Fundamental B-mode sonogram reveals complicated character of lesion with cystic and solid portions and thickened septal structures.

 


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Fig. 2B. Complicated cystic lesion with multiple partly thickened septations in 64-year-old woman. Contrast-enhanced CT scan (not shown) revealed complicated cystic lesion with solid septal portions. Lesion was not removed, and six monthly follow-up CT scans (not shown) did not show any changes over period of 1 year. Phase-inversion tissue harmonic image depicts internal structure of lesion more concisely. Phase-inversion tissue harmonic imaging enables depiction of multiple septations and differentiation of thickened septal parts and walls. Borders of adjacent parenchyma can be clearly delineated.

 


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Fig. 3A. 75-year-old man with small hemorrhagic cyst (12 mm in diameter) of left kidney. Fundamental B-mode sonogram shows hypoechoic lesion in which internal echoes are obscured by reverberation artifacts. Overall image quality is also degraded by acoustic scattering. Posterior acoustic enhancement is not shown with confidence.

 


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Fig. 3B. 75-year-old man with small hemorrhagic cyst (12 mm in diameter) of left kidney. Phase-inversion tissue harmonic image is better quality overall than A and has fewer scattering artifacts. Solid portion of lesion can be differentiated from fluid-filled part (arrow) with higher diagnostic confidence. Distinct distal acoustic enhancement is visible.

 


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Fig. 4A. 71-year-old man with transitional cell carcinoma (35 mm in diameter) of left kidney. Fundamental B-mode sonogram shows tumor of upper pole slightly hypoechoic to renal sinus fat. Distal border of process is not well defined.

 


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Fig. 4B. 71-year-old man with transitional cell carcinoma (35 mm in diameter) of left kidney. Phase-inversion tissue harmonic image has fewer scattering artifacts than A, especially in distal part of image. Because contrast resolution is better, tumor is better delineated. Distal border (arrow) and internal structure of solid process are visible.

 


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Fig. 5A. 45-year-old man with renal metastatic disease of small cell bronchial carcinoma (20 mm in diameter). Fundamental B-mode sonogram depicts suspicious hypoechoic lesion adjacent to right kidney.

 


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Fig. 5B. 45-year-old man with renal metastatic disease of small cell bronchial carcinoma (20 mm in diameter). Phase-inversion tissue harmonic image reveals solid character of exophytic mass clearly. Tumor shows hypoechoic rim (arrow) and tumorous bridge adjacent to renal cortex. Typical sonomorphologic features of kidney (sinus, medulla, and cortex) are also clearly delineated.

 

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