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Imaging of Severe Acute Respiratory Syndrome in Hong Kong

Gregory E. Antonio1, K. T. Wong1, David S. C. Hui2, Nelson Lee2, Edmund H. Y. Yuen1, Alan Wu2, Sydney S. C. Chung3, Joseph J. Y. Sung2 and Anil T. Ahuja1

1 Department of Diagnostic Radiology and Organ Imaging, Prince of Wales Hospital, Chinese University of Hong Kong, 30-32 Ngan Shing St., Shatin, Hong Kong Special Administrative Region, Republic of China.
2 Department of Medicine and Therapeutics, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, Hong Kong Special Administrative Region, Republic of China.
3 Department of Surgery, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, Hong Kong Special Administrative Region, Republic of China.



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Fig. 1A. Type 1 progression shown on serial chest radiographs of 38-year-old woman with 2-day history of fever and chills. Frontal chest radiograph obtained at presentation shows ill-defined air-space opacity in periphery of right lower zone.

 


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Fig. 1B. Type 1 progression shown on serial chest radiographs of 38-year-old woman with 2-day history of fever and chills. Frontal chest radiograph obtained on day 2 shows increase in extent of pulmonary opacity in right lower zone.

 


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Fig. 1C. Type 1 progression shown on serial chest radiographs of 38-year-old woman with 2-day history of fever and chills. Frontal chest radiograph obtained on day 7 shows further radiographic progression with additional ill-defined air-space opacity in left lower zone.

 


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Fig. 1D. Type 1 progression shown on serial chest radiographs of 38-year-old woman with 2-day history of fever and chills. Frontal chest radiograph obtained on day 12 shows resolution of pulmonary opacities in both lower zones.

 


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Fig. 2A. Type 2 progression shown on serial chest radiographs of 37-year-old man with 1-day history of high fever and cough. Frontal chest radiograph obtained at presentation shows subtle increased opacity in periphery of right lower zone.

 


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Fig. 2B. Type 2 progression shown on serial chest radiographs of 37-year-old man with 1-day history of high fever and cough. Frontal chest radiograph obtained on day 3 shows confluent air-space opacity in periphery of right lower zone that is more obvious than on previous radiograph (A).

 


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Fig. 2C. Type 2 progression shown on serial chest radiographs of 37-year-old man with 1-day history of high fever and cough. Frontal chest radiograph obtained on day 5 shows worsening of airspace opacities in right lower zone and involvement of left lower zone.

 


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Fig. 2D. Type 2 progression shown on serial chest radiographs of 37-year-old man with 1-day history of high fever and cough. Frontal chest radiograph obtained on day 12 shows resolution of bilateral lower zone pulmonary opacities.

 


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Fig. 2E. Type 2 progression shown on serial chest radiographs of 37-year-old man with 1-day history of high fever and cough. Frontal chest radiograph obtained on day 16 shows reappearance of multifocal ill-defined air-space opacities in mid and lower zones of both lungs. Subsequent follow-up radiograph obtained at discharge (not shown) revealed resolution of pulmonary opacities.

 


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Fig. 3A. Type 4 progression shown on serial chest radiographs of 83-year-old woman with 3-day history of fever, chills, and rigor. Frontal chest radiograph obtained at presentation shows area of ill-defined air-space opacity in right middle lobe obscuring part of right heart border.

 


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Fig. 3B. Type 4 progression shown on serial chest radiographs of 83-year-old woman with 3-day history of fever, chills, and rigor. Frontal chest radiograph obtained on day 2 shows increased area of pulmonary opacities in right lower zone. Subtle air-space opacities appear in perihilar regions of both upper zones.

 


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Fig. 3C. Type 4 progression shown on serial chest radiographs of 83-year-old woman with 3-day history of fever, chills, and rigor. Frontal chest radiograph obtained on day 5 shows progressive patchy areas of pulmonary opacities in both lungs.

 


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Fig. 3D. Type 4 progression shown on serial chest radiographs of 83-year-old woman with 3-day history of fever, chills, and rigor. Frontal chest radiograph obtained on day 10 shows further radiographic progression with adult respiratory distress syndrome—type of confluent opacification. Patient died 1 day after last radiograph.

 


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Fig. 4A. High-resolution CT scans show ground-glass opacification in two patients. CT scan of 33-year-old man shows large area of ground-glass opacification. Note that underlying pulmonary vasculature (arrow) is not obscured.

 


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Fig. 4B. High-resolution CT scans show ground-glass opacification in two patients. CT scan of 51-year-old woman shows multiple small areas of ground-glass opacification.

 


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Fig. 5. High-resolution CT scan of 52-year-old woman shows consolidation. Vascular architecture is obscured and air bronchograms are seen.

 


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Fig. 6. High-resolution CT scan of 61-year-old man shows mixed ground-glass and consolidated opacification. Air bronchogram (arrow) runs through center of consolidation (vascular architecture obscured). Note ground-glass opacification present at edges of consolidation.

 


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Fig. 7. High-resolution CT scan of 56-year-old man shows thickened interlobular septa and intralobular interstitium superimposed on ground-glass opacification.

 


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Fig. 8A. High-resolution CT scans and radiograph of 27-year-old woman with strong clinical suspicion of severe acute respiratory syndrome. CT scan shows crazy paving pattern (arrow) with markedly thickened interlobular septa superimposed on ground-glass opacification.

 


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Fig. 8B. High-resolution CT scans and radiograph of 27-year-old woman with strong clinical suspicion of severe acute respiratory syndrome. Chest radiograph shows no obvious abnormality.

 


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Fig. 8C. High-resolution CT scans and radiograph of 27-year-old woman with strong clinical suspicion of severe acute respiratory syndrome. CT scan obtained within 24 hr of initial CT scan shows left paraspinal opacity in left upper lobe posterior segment behind aortic arch.

 

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