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Correlation of Positron Emission Tomography and CT in Evaluating Pancreatic Tumors: Technical and Clinical Implications

¹ All authors: Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Founders House, 55 Fruit St., Boston, MA 02114.

View larger version (132K): [in a new window]   Fig. 1A. —50-year-old woman with biopsy-proven pancreatic adenocarcinoma. Positron emission tomography image shows intense FDG uptake in pancreatic bed (arrow).

View larger version (119K): [in a new window]   Fig. 1B. —50-year-old woman with biopsy-proven pancreatic adenocarcinoma. CT correlation scan shows soft-tissue mass (arrow) in pancreas that is suspicious for pancreatic malignancy and is encasing superior mesenteric artery.

View larger version (142K): [in a new window]   Fig. 2A. —58-year-old man after Whipple surgery. Contrast-enhanced CT image shows enhancing lesion (arrow) in segment VI of liver that is too small to characterize.

View larger version (116K): [in a new window]   Fig. 2B. —58-year-old man after Whipple surgery. Coronal image of positron emission tomography data shows intense FDG uptake in corresponding region (arrow).

View larger version (137K): [in a new window]   Fig. 2C. —58-year-old man after Whipple surgery. Contrast-enhanced CT scan acquired 6 months after B shows larger enhancing lesion (arrow) in same region, suggestive of metastasis.

View larger version (153K): [in a new window]   Fig. 3A. —Positron emission tomography (PET) and CT correlation in 72-year-old man with recurrence after Whipple surgery for pancreatic cancer. Contrast-enhanced CT image shows ill-defined soft-tissue mass (arrow) in pancreatic bed, involving celiac artery.

View larger version (142K): [in a new window]   Fig. 3B. —Positron emission tomography (PET) and CT correlation in 72-year-old man with recurrence after Whipple surgery for pancreatic cancer. Contrast-enhanced CT image shows mass (arrow) with portal vein thrombosis.

View larger version (98K): [in a new window]   Fig. 3C. —Positron emission tomography (PET) and CT correlation in 72-year-old man with recurrence after Whipple surgery for pancreatic cancer. Coronal PET image shows intense uptake of radiotracer FDG in pancreatic head region (arrow) suggestive of recurrent or residual tumor.

View larger version (101K): [in a new window]   Fig. 3D. —Positron emission tomography (PET) and CT correlation in 72-year-old man with recurrence after Whipple surgery for pancreatic cancer. PET image obtained in transverse plane shows increased metabolic activity (arrow) in pancreatic region suggestive of recurrent or residual tumor.

View larger version (18K): [in a new window]   Fig. 4. —Diagram shows proposed imaging algorithm for pancreatic cancer. PET = positron emission tomography.

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