AJR
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Abstract Freely available
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Sarlis, N. J.
Right arrow Articles by Patronas, N. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Sarlis, N. J.
Right arrow Articles by Patronas, N. J.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?
Hotlight (NEW!)
Right arrow
What's Hotlight?

MR Imaging Features of Thyrotropin-Secreting Pituitary Adenomas at Initial Presentation

Nicholas J. Sarlis1,2, Loukas Gourgiotis1, Christian A. Koch3,4, Monica C. Skarulis5, Françoise Brucker-Davis6, John L. Doppman7,8, Edward H. Oldfield9 and Nicholas J. Patronas7

1 Clinical Endocrinology Branch, National Institutes of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Rm. 8D04, Bldg. 10, 10 Center Dr., Bethesda, MD 20892.
2 Present address: Department of Endocrine Neoplasia and Hormonal Disorders, The University of Texas M. D. Anderson Cancer Center, Unit 435, 1515 Holcombe Blvd., Houston, TX 77030-4009.
3 Pediatric and Reproductive Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Rm. 9D42, Bldg. 10, 10 Center Dr., Bethesda, MD 20892.
4 Present address: Department of Medicine III, University of Leipzig, Phillip-Rosenthal-Str. 27, Leipzig, D-04103, Germany.
5 Division of Intramural Research, National Institutes of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Rm. 8D12C, Bldg. 10, 10 Center Dr., Bethesda, MD 20892.
6 Department of Endocrine Medicine and Diabetes, Centre Hospitalier de l'Université de Nice (CHUN), Nice, Cedex 01, F-06002, France.
7 Department of Radiology, Warren G. Magnuson Clinical Center, National Institutes of Health, Rm. 1C635, Bldg. 10, 10 Center Dr., Bethesda, MD 20892.
8 Deceased.
9 Surgical Neurology Branch, National Institute of Neurological Diseases and Stroke, National Institutes of Health, Rm. 5D37, Bldg. 10, 10 Center Dr., Bethesda, MD 20892.



View larger version (27K):

[in a new window]
  		Fig. 1. —Drawing shows staging system for thyrotropin-producing pituitary adenomas used in our study. ICA = internal carotid artery, CSI = cavernous sinus invasion, SSI = sphenoid sinus invasion, SSE = suprasellar extension.

 


View larger version (120K):

[in a new window]
  		Fig. 2. —38-year-old woman with thyrotropin-producing pituitary adenoma. MR image shows hypoenhancing appearance of microadenoma (arrow) with regard to normal pituitary gland.

 


View larger version (137K):

[in a new window]
  		Fig. 3. —46-year-old-man with thyrotropin-producing pituitary adenoma. MR image shows grade 2 cavernous sinus invasion and grade 2 sphenoid sinus invasion (arrow) by tumor.

 


View larger version (155K):

[in a new window]
  		Fig. 4. —57-year-old woman with thyrotropin-producing pituitary adenoma. MR image shows grade 2 cavernous sinus invasion (black arrow) and grade 3 suprasellar extension (white arrow) of tumor.

 


View larger version (131K):

[in a new window]
  		Fig. 5. —50-year-old woman with thyrotropin-producing pituitary adenoma. MR image shows grade 3 suprasellar tumor extension and significant distortion of normal pituitary anatomy (arrows) (capping).

 


View larger version (133K):

[in a new window]
  		Fig. 6A. —48-year-old woman with thyrotropin-producing pituitary adenoma. MR image obtained in coronal plane shows grade 3 tumor invasion in both suprasellar space (black arrowheads) and sphenoid sinus (white arrowhead).

 


View larger version (115K):

[in a new window]
  		Fig. 6B. —48-year-old woman with thyrotropin-producing pituitary adenoma. MR image obtained in lateral plane shows grade 3 tumor invasion in both suprasellar space (black arrowhead) and sphenoid sinus (white arrowheads).

 


View larger version (124K):

[in a new window]
  		Fig. 6C. —48-year-old woman with thyrotropin-producing pituitary adenoma. MR image obtained in coronal plane (more posteriorly located than A) shows grade 3 tumor invasion in all three axes: suprasellar space (black arrowhead), cavernous sinuses bilaterally (black arrows), and sphenoid sinus (white arrows).

 


View larger version (17K):

[in a new window]
  		Fig. 7. —Graph shows correlation between tumor volume in cubic centimeters and cumulative score according to staging system used in our study. As expected, strong positive log-linear correlation is evident, along with 95% confidence interval curves for this correlation.

 

Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?



HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2003 by the American Roentgen Ray Society.