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Computer-Aided Detection (CAD) in Screening Mammography: Sensitivity of Commercial CAD Systems for Detecting Architectural Distortion

Jay A. Baker1, Eric L. Rosen, Joseph Y. Lo, Edgardo I. Gimenez, Ruth Walsh and Mary Scott Soo

1 All authors: Department of Radiology, Duke University Medical Center, Box 3808, Durham, NC 27710.



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  		Fig. 1A. —59-year-old woman with invasive ductal carcinoma of right breast. Architectural distortion seen on images was successfully detected and marked by only one of two computer-aided detection systems tested. Craniocaudal mammogram shows typical appearance of architectural distortion (box): radiating lines without central density.

 


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  		Fig. 1B. —59-year-old woman with invasive ductal carcinoma of right breast. Architectural distortion seen on images was successfully detected and marked by only one of two computer-aided detection systems tested. Mediolateral oblique mammogram also shows architectural distortion (box).

 


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  		Fig. 1C. —59-year-old woman with invasive ductal carcinoma of right breast. Architectural distortion seen on images was successfully detected and marked by only one of two computer-aided detection systems tested. Spot compression magnification image of right breast shows lack of central density at site of distortion (arrow) more clearly than do mammograms A and B.

 


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  		Fig. 2A. —55-year-old woman with ductal carcinoma in situ of left breast. Architectural distortion was successfully identified by interpreting radiologist but was not detected by either computer-aided detection system. Craniocaudal mammogram shows subtle architectural distortion (box) in lateral aspect of breast. Note radiating lines without central mass in dense breast parenchyma.

 


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  		Fig. 2B. —55-year-old woman with ductal carcinoma in situ of left breast. Architectural distortion was successfully identified by interpreting radiologist but was not detected by either computer-aided detection system. Mediolateral oblique mammogram shows more conspicuous architectural distortion (box) than craniocaudal view (A). No central density is present.

 


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  		Fig. 2C. —55-year-old woman with ductal carcinoma in situ of left breast. Architectural distortion was successfully identified by interpreting radiologist but was not detected by either computer-aided detection system. Specimen radiograph from wire-localized surgical excision confirms architectural distortion (arrow) centered on middle of thickened wire. No mass or associated calcifications are seen.

 

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