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Acceptance by Patients of Multidetector CT Colonography Compared with Barium Enema Examinations, Flexible Sigmoidoscopy, and Colonoscopy

Stuart A. Taylor1, Steve Halligan1,2, Brian P. Saunders3, Paul Bassett1, Maggie Vance3 and Clive I. Bartram1

1 Department of Intestinal Imaging, Intestinal Imaging Centre, Level 4V, St. Mark's Hospital, Watford Rd., Northwick Park, London HA1 3UJ, United Kingdom.
2 Cancer Research UK Colorectal Cancer Unit, St. Mark's Hospital, Northwick Park, London HA1 3UJ, United Kingdom.
3 Wolfson Institute of Endoscopy, St. Mark's Hospital, Northwick Park, London HA1 3UJ, United Kingdom.



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  		Fig. 1. —Graph depicts median score and interquartile range for three principal components for patients undergoing multidetector CT colonography ({circ}) and colonoscopy ({blacktriangleup}). Higher score reflects more positive patient response. Patients reported statistically significant greater satisfaction but more physical discomfort with colonoscopy than with CT colonography (p < 0.01 [asterisks]).

 


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  		Fig. 2. —Graph depicts median score and interquartile range for three principal components for patients undergoing multidetector CT colonography ({circ}) and flexible sigmoidoscopy ({blacksquare}). Higher score reflects more positive patient response. No significant difference was seen in overall responses between CT colonography and flexible sigmoidoscopy for each principal component.

 


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  		Fig. 3. —Graph depicts median score and interquartile range for three principal components for patients undergoing barium enema ({square}) compared with those undergoing multidetector CT colonography ({circ}), colonoscopy ({blacktriangledown}), and flexible sigmoidoscopy ({blacksquare}). Higher score reflects more positive patient response. Quoted p values are derived from comparison of barium enema scores with each other procedure. Barium enema resulted in significantly worse scores for each principal component than did CT colonography, colonoscopy, or flexible sigmoidoscopy (p < 0.05 [single asterisks], p < 0.001 [double asterisks]).

 


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  		Fig. 4. —Bar graph illustrates responses to follow-up questionnaire from patients undergoing multidetector CT colonography (white bars) and colonoscopy (black bars) (n = 91 replies). Significantly more patients tolerated CT colonography well than tolerated colonoscopy well. Patients expressing a preference (n = 55) significantly preferred CT colonography to colonoscopy; and of those expressing an opinion (n = 60), significantly more found CT colonography more acceptable (p < 0.005 [asterisks]).

 


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  		Fig. 5. —Bar graph illustrates responses to follow-up questionnaire from patients undergoing multidetector CT colonography (white bars) and flexible sigmoidoscopy (black bars) (n = 38 replies). Patients were significantly less likely to undergo sigmoidoscopy again than CT colonography. Of those expressing preference (n = 22), significantly more preferred CT colonography to sigmoidoscopy; and significantly more of those patients expressing opinion (n = 20) found CT colonography more acceptable (p < 0.05 [single asterisks], p < 0.005 [double asterisks]).

 

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