AJR
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Asad, S.
Right arrow Articles by Fischman, A. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Asad, S.
Right arrow Articles by Fischman, A. J.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?

False-Positive FDG Positron Emission Tomography Uptake in Nonmalignant Chest Abnormalities

Syed Asad1, Suzanne L. Aquino2, Nitra Piyavisetpat2 and Alan J. Fischman2

1 Department of Neurology, Emory University Hospital, 1639 Pierce Dr., WMRB 6009, Atlanta, GA 30322.
2 Department of Radiology, Massachusetts General Hospital, 55 Fruit St., FND 202, Boston, MA 02114.



View larger version (112K):

[in a new window]
  		Fig. 1A. —59-year-old man with pulmonary mass. CT scan shows 7-cm round mass (arrow) in right lower lobe that involves lung and pleura.

 


View larger version (102K):

[in a new window]
  		Fig. 1B. —59-year-old man with pulmonary mass. FDG positron emission tomography image shows increased uptake (arrow) suggestive of neoplasm. Surgical pathology revealed bronchial cartilaginous hamartoma. Theoretically, hamartoma should not show increased uptake of FDG. In this example, when FDG is increased, further diagnosis by biopsy or resection is warranted.

 


View larger version (121K):

[in a new window]
  		Fig. 2A. —67-year-old man with newly diagnosed pulmonary nodule. CT scan shows ill-defined nodule (arrow) in left lung.

 


View larger version (106K):

[in a new window]
  		Fig. 2B. —67-year-old man with newly diagnosed pulmonary nodule. FDG positron emission tomography image shows increased uptake (arrow) suggestive of malignancy. Nodule was resected and showed organizing pneumonia.

 


View larger version (141K):

[in a new window]
  		Fig. 3A. —62-year-old man with history of lung cancer and severe emphysema. CT scan shows spiculated nodule (arrow) suggestive of either new primary tumor or recurrent disease.

 


View larger version (78K):

[in a new window]
  		Fig. 3B. —62-year-old man with history of lung cancer and severe emphysema. FDG positron emission tomography image of thorax shows increased radiotracer uptake of FDG in nodule (arrow). Wedge resection was performed. Nodule was caused by atypical mycobacterial infection.

 


View larger version (101K):

[in a new window]
  		Fig. 4A. —69-year-old woman with multiple pulmonary nodules. CT scan shows multiple small- and intermediate-sized nodules (arrows) in both lungs.

 


View larger version (123K):

[in a new window]
  		Fig. 4B. —69-year-old woman with multiple pulmonary nodules. FDG positron emission tomography image shows multiple foci of increased uptake (arrows) in lungs. Biopsy showed epithelioid granulomas consistent with sarcoidosis.

 


View larger version (95K):

[in a new window]
  		Fig. 5. —24-year-old woman with newly diagnosed lymphadenopathy in thorax. FDG positron emission tomography image shows multiple areas of increased uptake in mediastinal and hilar lymph nodes (arrows). Surgical biopsy showed sarcoidosis. Diffuse FDG uptake in enlarged thoracic lymph nodes suggests lymphoma. Presence of lymphadenopathy combined with parenchymal abnormalities in bilateral upper lobe distribution suggests sarcoidosis.

 


View larger version (135K):

[in a new window]
  		Fig. 6A. —72-year-old woman with history of breast cancer and newly diagnosed pulmonary nodules. CT scan shows multiple nodules (arrows) and associated parenchymal cysts (arrowheads). Some nodules contain calcium.

 


View larger version (121K):

[in a new window]
  		Fig. 6B. —72-year-old woman with history of breast cancer and newly diagnosed pulmonary nodules. FDG positron emission tomography image shows increased uptake in nodule (arrow) in right lower lobe. This nodule was biopsied and showed amyloid on Congo red stain.

 


View larger version (102K):

[in a new window]
  		Fig. 7A. —68-year-old woman with history of breast cancer and talc pleurodesis 10 years earlier. CT scan shows dense nodular pleural thickening (arrows) in right lower thorax adjacent to esophagus and inferior vena cava.

 


View larger version (93K):

[in a new window]
  		Fig. 7B. —68-year-old woman with history of breast cancer and talc pleurodesis 10 years earlier. FDG positron emission tomography (PET) image shows increased uptake in nodules (arrows). CT scan should be available to correlate areas of hypermetabolism on PET with regions of dense talc deposits to avoid false-positive interpretation. These nodules were stable on sequential CT scans for more than 5 years.

 


View larger version (142K):

[in a new window]
  		Fig. 8A. —68-year-old man with pulmonary nodule and history of asbestos pleural disease. CT scan shows 3-cm subpleural nodule (arrow) in right upper lobe adjacent to pleural plaque (arrowhead).

 


View larger version (67K):

[in a new window]
  		Fig. 8B. —68-year-old man with pulmonary nodule and history of asbestos pleural disease. FDG positron emission tomography image of upper thorax shows increased uptake in nodule (arrow). This nodule was resected, and pathologic findings were consistent with round atelectasis.

 


View larger version (115K):

[in a new window]
  		Fig. 9A. —71-year-old man with weight loss and chronic heart disease. CT scan of thorax revealed bilateral pleural thickening (arrows) suggesting malignancy.

 


View larger version (124K):

[in a new window]
  		Fig. 9B. —71-year-old man with weight loss and chronic heart disease. Coronal FDG positron emission tomography image shows increased uptake (arrows) in right pleura. Surgical biopsy showed organizing fibrinous pleuritis and fibrosis in pleura. No malignancy was found.

 


View larger version (91K):

[in a new window]
  		Fig. 10A. —60-year-old woman with lung cancer. FDG positron emission tomography (PET) image shows multiple areas of increased uptake (arrows) in superior mediastinum suggestive of diffuse nodal disease.

 


View larger version (68K):

[in a new window]
  		Fig. 10B. —60-year-old woman with lung cancer. Fusion of PET image and CT scan of that increased uptake (arrow) corresponds to left common carotid artery.

 


View larger version (79K):

[in a new window]
  		Fig. 10C. —60-year-old woman with lung cancer. CT scan without fusion of PET image of vascular anatomy shows contrast-enhanced left common carotid artery (arrow). Mediastinoscopy confirmed no evidence of mediastinal metastatic disease.

 

Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?



HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2004 by the American Roentgen Ray Society.