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Characterization of Focal Liver Lesions in Real Time Using Harmonic Imaging with High Mechanical Index and Contrast Agent Levovist

¹ All authors: Sardinian Mediterranean Imaging Research Group, Via Gorizia no. 11, Sassari 07100, Sardinia, Italy.

View larger version (149K): [in a new window]   Fig. 1A. —67-year-old man with cirrhosis and hepatocellular carcinoma. Arterial phase flash sonogram shows early enhancement of lesion.

View larger version (138K): [in a new window]   Fig. 1B. —67-year-old man with cirrhosis and hepatocellular carcinoma. Portal phase flash sonogram shows increased enhancement in comparison with surrounding parenchyma.

View larger version (177K): [in a new window]   Fig. 1C. —67-year-old man with cirrhosis and hepatocellular carcinoma. Parenchymal phase flash sonogram shows early washout of contrast material in lesion in comparison with surrounding parenchyma.

View larger version (147K): [in a new window]   Fig. 1D. —67-year-old man with cirrhosis and hepatocellular carcinoma. Sonogram obtained during real-time vascular evaluation in arterial phase shows arterial segmental branch (arrow) from which irregular microvessels arise.

View larger version (126K): [in a new window]   Fig. 2A. —9-year-old girl with focal nodular hyperplasia. Arterial phase flash sonogram shows early enhancement of lesion.

View larger version (117K): [in a new window]   Fig. 2B. —9-year-old girl with focal nodular hyperplasia. Portal phase flash sonogram shows enhancement of lesion similar to surrounding parenchyma.

View larger version (146K): [in a new window]   Fig. 2C. —9-year-old girl with focal nodular hyperplasia. Parenchymal phase flash sonogram shows no apparent washout.

View larger version (123K): [in a new window]   Fig. 2D. —9-year-old girl with focal nodular hyperplasia. Sonogram obtained during real-time vascular evaluation shows "central spider" sign.

View larger version (131K): [in a new window]   Fig. 3A. —28-year-old woman with hemangioma. Arterial phase flash sonogram shows rim enhancement.

View larger version (138K): [in a new window]   Fig. 3B. —28-year-old woman with hemangioma. Portal phase flash sonogram shows progressive lobular enhancement in centripetal direction.

View larger version (136K): [in a new window]   Fig. 3C. —28-year-old woman with hemangioma. Parenchymal phase flash sonogram shows almost complete fill-in.

View larger version (155K): [in a new window]   Fig. 3D. —28-year-old woman with hemangioma. Sonogram obtained during real-time vascular evaluation shows microvessels in peripheral zone (arrow).

View larger version (141K): [in a new window]   Fig. 4A. —63-year-old man with metastatic liver disease. Arterial phase flash sonogram shows inhomogeneous and low enhancement of lesion.

View larger version (137K): [in a new window]   Fig. 4B. —63-year-old man with metastatic liver disease. Portal phase flash sonogram shows slightly less enhancement.

View larger version (156K): [in a new window]   Fig. 4C. —63-year-old man with metastatic liver disease. Parenchymal phase flash sonogram shows complete lack of enhancement.

View larger version (149K): [in a new window]   Fig. 4D. —63-year-old man with metastatic liver disease. Sonogram obtained during real-time vascular evaluation shows poor vasculature of lesions.

View larger version (162K): [in a new window]   Fig. 5A. —65-year-old man with cirrhosis and regenerating nodule. Arterial phase flash sonogram shows no enhancement of lesion.

View larger version (126K): [in a new window]   Fig. 5B. —65-year-old man with cirrhosis and regenerating nodule. Portal phase flash sonogram shows homogeneous enhancement in comparison with surrounding parenchyma.

View larger version (136K): [in a new window]   Fig. 5C. —65-year-old man with cirrhosis and regenerating nodule. Parenchymal phase flash sonogram shows no evident washout.

View larger version (127K): [in a new window]   Fig. 5D. —65-year-old man with cirrhosis and regenerating nodule. Sonogram obtained during real-time vascular evaluation shows no apparent vessels in lesion.

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