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Imaging of Ancient Schwannoma

Kenichi Isobe1, Tominaga Shimizu, Tsutomu Akahane and Hiroyuki Kato

1 All authors: Department of Orthopedic Surgery, Shinshu University, School of Medicine, 3-1-1 Asahi, Matsumoto, Nagano 390-8621, Japan.



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Fig. 1A. CT evaluation in 80-year-old woman with ancient schwannoma. Axial CT scan of lower leg shows large, well-circumscribed low-density mass with partial central high-density area in posterior compartment.

 


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Fig. 1B. CT evaluation in 80-year-old woman with ancient schwannoma. Contrast-enhanced CT scan shows enhancement in circumference of degenerative area and peripheral rim.

 


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Fig. 2D. MRI and histologic findings in 60-year-old man with ancient schwannoma. Photograph shows gross appearance of tumor. Squares show circumference of degenerative areas (E), area of degenerative change (F), and substance (G).

 


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Fig. 3D. MRI and histologic findings in 56-year-old woman with ancient schwannoma. Photograph of gross appearance of tumor shows marked degeneration.

 


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Fig. 2A. MRI and histologic findings in 60-year-old man with ancient schwannoma. Axial T1-weighted MR image shows large well-circumscribed mass with isointense signal. Note round high-signal-intensity area (arrow) in mass.

 


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Fig. 2B. MRI and histologic findings in 60-year-old man with ancient schwannoma. T2-weighted image shows most of tumor as hyperintense signal and partially heterogeneous signal in internal oval area. Note areas of Antoni A (arrow) and Antoni B (arrowhead) tumor.

 


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Fig. 2C. MRI and histologic findings in 60-year-old man with ancient schwannoma. Gadolinium contrast-enhanced image shows enhancement at circumference of degenerative lesion (arrow), peripheral rim (arrowhead), and substantial part.

 


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Fig. 2E. MRI and histologic findings in 60-year-old man with ancient schwannoma. Photomicrograph shows Antoni A area. (H and E, x100)

 


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Fig. 2F. MRI and histologic findings in 60-year-old man with ancient schwannoma. Photomicrograph clearly shows hematoma and degenerative collagen tissue. (H and E, x100)

 


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Fig. 2G. MRI and histologic findings in 60-year-old man with ancient schwannoma. Photomicrograph clearly shows Antoni B area. (H and E, x100)

 


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Fig. 3A. MRI and histologic findings in 56-year-old woman with ancient schwannoma. Axial T1-weighted MR image of adductor magnus shows large tumor with isointense signal.

 


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Fig. 3B. MRI and histologic findings in 56-year-old woman with ancient schwannoma. T2-weighted image shows heterogeneous tumor with high signal intensity in internal oval area (arrow).

 


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Fig. 3C. MRI and histologic findings in 56-year-old woman with ancient schwannoma. Gadolinium contrast-enhanced image shows enhancement in circumference of degenerative area (arrowhead) and peripheral rim of tumor (star). Oval degenerative area (arrow) is not enhanced.

 

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