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Impact of Fusion of Indium-111 Capromab Pendetide Volume Data Sets with Those from MRI or CT in Patients with Recurrent Prostate Cancer

Chris J. Schettino1,2, Elissa L. Kramer1,3, Marilyn E. Noz1, Samir Taneja4, Priya Padmanabhan4 and Herbert Lepor4

1 Department of Radiology, New York University School of Medicine, New York, NY 10016.
3 Department of Nuclear Medicine, New York University Medical Center, Tisch Hospital, 550 First Ave., HW 231, New York, NY 10016.
4 Department of Urology, New York University School of Medicine, New York, NY 10016.



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Fig. 1. —Example of fused volume showing slices in all three orthogonal planes. Slices on left are original floating volume. Slices in middle show transformed floating volume superimposed on and blended with original CT volume (note match of bone structures, especially on sagittal view in bottom row). Slices on right show original CT volume.

 


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Fig. 2. —Fused image showing false-positive Prosta-Scint (Cytogen) study. Uptake originally thought to represent lymph nodes was found after fusion to be vessel (1, arrow) and bowel (2, arrow) uptake on fusion. Upper panel shows original Prosta-Scint transverse slice, and lower panel shows Prosta-Scint transverse slice fused and superimposed on matching MRI slice.

 


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Fig. 3. —Fused image showing true-positive Prosta-Scint (Cytogen) uptake. Uptake was found after fusion to represent disease in lymph node (arrows). Upper panel shows original Prosta-Scint transverse slice, and lower panel shows Prosta-Scint transverse slice fused and superimposed on matching MRI slice.

 

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