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Contrast-Enhanced Sonographic Appearance of Hepatocellular Carcinoma in Patients with Cirrhosis: Comparison with Contrast-Enhanced Helical CT Appearance

¹ All authors: Interventional Ultrasound Service, D. Cotugno Hospital, Via Quagliariello 54, Naples 84100, Italy.

View larger version (142K): [in a new window]   Fig. 1A. —62-year-old woman with hepatocellular carcinoma and liver cirrhosis. Subcostal unenhanced sonogram of liver shows nodule in hepatic segment VIII with no power Doppler signal in either central or peripheral portion of tumor.

View larger version (143K): [in a new window]   Fig. 1B. —62-year-old woman with hepatocellular carcinoma and liver cirrhosis. Contrast-enhanced sonogram obtained during early arterial phase (16 sec after IV contrast injection) of same area of liver seen in A shows that nodular lesion has become intensely hyperechoic with homogeneous pattern.

View larger version (156K): [in a new window]   Fig. 1C. —62-year-old woman with hepatocellular carcinoma and liver cirrhosis. On contrast-enhanced sonogram obtained during portal phase (44 sec after IV contrast injection), nodule appears isoechoic relative to surrounding liver parenchyma.

View larger version (155K): [in a new window]   Fig. 1D. —62-year-old woman with hepatocellular carcinoma and liver cirrhosis. On contrast-enhanced sonogram obtained during late portal phase (54 sec after IV contrast injection), liver nodule is hypoechoic.

View larger version (154K): [in a new window]   Fig. 2A. —55-year-old man with hepatocellular carcinoma and liver cirrhosis. Subcostal unenhanced sonogram of liver shows nodular isoechoic lesion displaying peripheral power Doppler signals and no intratumoral vascular spots.

View larger version (175K): [in a new window]   Fig. 2B. —55-year-old man with hepatocellular carcinoma and liver cirrhosis. Contrast-enhanced sonogram obtained during portal phase (48 sec after IV contrast injection) shows delayed enhancement of liver lesion with reticular and heterogeneous pattern.

View larger version (141K): [in a new window]   Fig. 2C. —55-year-old man with hepatocellular carcinoma and liver cirrhosis. On contrast-enhanced sonogram, hypervascular reticular pattern of nodule (arrows) persists during sinusoidal phase (173 sec after IV contrast injection).

View larger version (170K): [in a new window]   Fig. 2D. —55-year-old man with hepatocellular carcinoma and liver cirrhosis. On contrast-enhanced sonogram obtained 239 sec after IV contrast injection, reticular pattern of nodule (arrows) is still evident.

View larger version (137K): [in a new window]   Fig. 3A. —71-year-old man with hepatocellular carcinoma and liver cirrhosis. Subcostal unenhanced sonogram of liver shows hypoechoic nodule in hepatic segment VII.

View larger version (159K): [in a new window]   Fig. 3B. —71-year-old man with hepatocellular carcinoma and liver cirrhosis. On sonogram obtained after IV contrast injection, no enhancement of nodular lesion is observed during portal phase. Tumor has become anechoic with respect to surrounding liver parenchyma.

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