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Differentiation of Renal Clear Cell Carcinoma and Renal Papillary Carcinoma Using Quantitative CT Enhancement Parameters

¹ Department of Radiology, University Hospital Graz, Auenbruggerplatz 9, Graz, Styria A-8036, Austria.
² Department of Radiology, Hospital of Leoben, A-8700 Leoben, Austria.
³ D2K-Solutions, A-8410 Wildon, Austria.

View larger version (154K): [in a new window]   Fig. 1. —Attenuation measurement of renal clear cell carcinoma on CT. Region of interest (ROI) is laid in lesion (different ROIs in solid and necrotic or cystic parts) to determine attenuation values of lesion (Lx). For quantitative evaluation, attenuation of solid part gives contrast enhancement of lesion. Another ROI is identified in aorta at level of origin of renal artery that supplies kidney with tumor, giving attenuation (Ax).

View larger version (66K): [in a new window]   Fig. 2A. —CT scans of renal clear cell carcinoma in left kidney show exophytic growing tumor with inhomogeneous contrast enhancement. Attenuation values (in Hounsfield units) in unenhanced phase (A), corticomedullary phase (B), and nephrographic phase (C) in triphasic helical CT are illustrated numerically in images in solid part of lesion.

View larger version (89K): [in a new window]   Fig. 2B. —CT scans of renal clear cell carcinoma in left kidney show exophytic growing tumor with inhomogeneous contrast enhancement. Attenuation values (in Hounsfield units) in unenhanced phase (A), corticomedullary phase (B), and nephrographic phase (C) in triphasic helical CT are illustrated numerically in images in solid part of lesion.

View larger version (92K): [in a new window]   Fig. 2C. —CT scans of renal clear cell carcinoma in left kidney show exophytic growing tumor with inhomogeneous contrast enhancement. Attenuation values (in Hounsfield units) in unenhanced phase (A), corticomedullary phase (B), and nephrographic phase (C) in triphasic helical CT are illustrated numerically in images in solid part of lesion.

View larger version (91K): [in a new window]   Fig. 3A. —CT scans of renal papillary carcinoma in left kidney show homogeneous tumor within parenchyma of left kidney. Attenuation values (in Hounsfield units) in unenhanced phase (A), corticomedullary phase (B), and nephrographic phase (C) in triphasic helical CT are shown numerically in images.

View larger version (88K): [in a new window]   Fig. 3B. —CT scans of renal papillary carcinoma in left kidney show homogeneous tumor within parenchyma of left kidney. Attenuation values (in Hounsfield units) in unenhanced phase (A), corticomedullary phase (B), and nephrographic phase (C) in triphasic helical CT are shown numerically in images.

View larger version (90K): [in a new window]   Fig. 3C. —CT scans of renal papillary carcinoma in left kidney show homogeneous tumor within parenchyma of left kidney. Attenuation values (in Hounsfield units) in unenhanced phase (A), corticomedullary phase (B), and nephrographic phase (C) in triphasic helical CT are shown numerically in images.

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