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Aortic Valve Calcification as a Marker for Aortic Stenosis Severity: Assessment on 16-MDCT

¹ Department of Cardiology, University Hospital Aachen, Pauwelsstraße 30, Aachen 52072, Germany.
² Department of Diagnostic Radiology, University Hospital Aachen, Aachen 52072, Germany.

View larger version (15K): [in a new window]   Fig. 1. —Graph shows box plots indicating median (horizontal line within box) and 25th–75th percentiles for aortic Agatston score in relation to stenosis severity determined at cardiac catheterization. Bars above and below boxes indicate minimum and maximum scores.

View larger version (13K): [in a new window]   Fig. 2. —Graph shows box plots indicating median (horizontal line within box) and 25th–75th percentiles for aortic mass score in relation to invasively determined stenosis severity. Dot above boxes represents single outlier. Bars above and below boxes indicate minimum and maximum scores.

View larger version (14K): [in a new window]   Fig. 3. —Graph shows box plots including median (horizontal line within box) and 25th–75th percentiles for aortic volume score in relation to stenosis severity determined at cardiac catheterization. Bars above and below boxes indicate minimum and maximum scores.

View larger version (154K): [in a new window]   Fig. 4. —72-year-old man with mild aortic stenosis assessed at cardiac catheterization. Multiplanar reformation of axial MDCT scans shows mild calcification of aortic valve leaflets (aortic Agatston score 807, aortic volume score 663, aortic mass score 155). Locations of right ventricle (RV), left ventricle (LV), right atrium (RA), and left atrium (LA) are indicated.

View larger version (127K): [in a new window]   Fig. 5. —68-year-old man with moderate aortic stenosis assessed at cardiac catheterization. Multiplanar reformation of axial MDCT scans shows moderate calcification of aortic valve leaflets (aortic Agatston score 1,949; aortic volume score 1,597; aortic mass score 467). Locations of right ventricle (RV), left ventricle (LV), right atrium (RA), and left atrium (LA) are indicated.

View larger version (145K): [in a new window]   Fig. 6. —78-year-old man with severe aortic stenosis assessed at cardiac catheterization. Multiplanar reformation of axial MDCT scans shows severe calcifications of all aortic valve leaflets (aortic Agatston score 7,750; aortic volume score 5,949; aortic mass score 1,630). Locations of right ventricle (RV), left ventricle (LV), right atrium (RA), and left atrium (LA) are indicated.

View larger version (9K): [in a new window]   Fig. 7. —Graph shows receiver operating curve (ROC) for aortic mass score. Area under ROC curve for aortic mass scores is 0.91, indicating that test has high degree of accuracy for distinguishing patients with severe stenosis from those with mild or moderate aortic stenosis.

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