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Accuracy of CT in the Diagnosis of Pulmonary Embolism: A Systematic Literature Review

John Eng1, Jerry A. Krishnan2, Jodi B. Segal2, Dennis T. Bolger2, Leonardo J. Tamariz2, Michael B. Streiff2, Mollie W. Jenckes2 and Eric B. Bass2,3

1 Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 600 N Wolfe St., Central Radiology Viewing Area, Rm. 117, Baltimore, MD 21287.
2 Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287.
3 Department of Health Policy and Management, Johns Hopkins University Bloomberg School of Public Health, 615 N Wolfe St., Baltimore, MD 21205.



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  		Fig. 1. —Plot of true-positive rate (sensitivity, proportion of those with pulmonary embolism who have positive test result) versus false-positive rate (1 – specificity, proportion of those without pulmonary embolism who have erroneously positive test result) of eight primary studies evaluating use of CT for diagnosis of pulmonary embolism.

 


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  		Fig. 2. —Plot of sensitivity and specificity versus prevalence reported in primary studies evaluating use of CT for diagnosis of pulmonary embolism. = sensitivity, = specificity.

 


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  		Fig. 3. —Plot of sensitivity and specificity of CT reported in primary studies in chronologic order of publication. Because all studies were published at 1- to 2-year intervals, horizontal axis is approximate time axis. = sensitivity, = specificity.

 

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