Gastrointestinal Schwannomas: CT Features with Clinicopathologic Correlation
Angela D. Levy1,2,
Ana M. Quiles3,
Markku Miettinen4 and
Leslie H. Sobin5
1 Department of Radiologic Pathology, Armed Forces Institute of Pathology, 6825
16th St., NW, Washington, DC 20306-6000.
2 Department of Radiology and Nuclear Medicine, Uniformed Services University of
the Health Sciences, Bethesda, MD 20814-4799.
3 Department of Radiology, UDIAT Diagnostic Center, Parc Tauli, Sabadell 08208,
Spain.
4 Department of Soft Tissue Pathology, Armed Forces Institute of Pathology,
Washington, DC.
5 Department of Gastrointestinal Pathology, Armed Forces Institute of Pathology,
Washington, DC.
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Fig. 1A. —Histologic features of gastrointestinal schwannomas. Photomicrograph
of small-intestinal schwannoma from 67-year-old man shows spindle cell tumor
with peripheral lymphoid cuff that contains germinal center (arrow).
(H and E)
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Fig. 1B. —Histologic features of gastrointestinal schwannomas. Photomicrograph
of gastric schwannoma from 82-year-old woman shows spindle cells organized in
microtrabecular pattern with alternating strands of tumor cells and stroma.
Wavy collagen is interspersed between tumor cells. (H and E)
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Fig. 2A. —Gastric schwannoma in 66-year-old woman who complained of abdominal
pain and early satiety. IV contrast–enhanced CT scan obtained during
portal venous phase of contrast enhancement shows round, homogeneous,
low-attenuation, 6.0-cm mass arising from lesser curvature of gastric fundus.
Mass extends into gastrohepatic ligament.
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Fig. 2B. —Gastric schwannoma in 66-year-old woman who complained of abdominal
pain and early satiety. Photograph of bivalved resected specimen shows
unencapsulated, homogeneous tumor in gastric wall.
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Fig. 3. —Incidentally discovered gastric schwannoma in 54-year-old woman who
underwent CT for bladder cancer staging. CT scan obtained during equilibrium
phase of contrast enhancement shows homogeneously enhancing 6.0-cm mass
arising from posterior body of stomach. Mass extends posterior to stomach and
has ulcer along its intraluminal margin (arrow).
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Fig. 4A. —Gastric schwannoma in 71-year-old woman who presented with
gastrointestinal bleeding. Unenhanced CT scan shows homogeneous, round mass
arising from greater curvature of body of stomach. Mass projects into gastric
lumen and has focal ulcer along its luminal margin (arrow).
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Fig. 4B. —Gastric schwannoma in 71-year-old woman who presented with
gastrointestinal bleeding. Photograph of cut surface of resected surgical
specimen shows ulcer (arrow) along mucosal margin tumor. Scale:
centimeters.
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Fig. 5A. —Small intestinal schwannoma in 95-year-old woman who complained of
nausea, vomiting, and abdominal pain. IV contrast–enhanced CT scan
obtained during equilibrium phase of contrast enhancement shows 2.5-cm round,
well-defined, homogeneously enhancing mural mass that projects into lumen of
dilated segment of small intestine.
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Fig. 5B. —Small intestinal schwannoma in 95-year-old woman who complained of
nausea, vomiting, and abdominal pain. Photograph of cut surface of resected
surgical specimen shows pale yellow, unencapsulated mass projecting into
intestinal lumen. Scale: centimeters.
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Fig. 6. —Esophageal schwannoma in 56-year-old woman with dysphagia. CT scan
shows nonenhancing round esophageal mass extends into mediastinum and deviates
esophageal lumen to right.
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Copyright © 2005 by the American Roentgen Ray Society.
