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Malignant Fibrous Histiocytoma of the Pharynx

Paras Lakhani1, Stephen E. Rubesin2 and Paul J. Zhang3

1 University of Pennsylvania School of Medicine, Philadelphia, PA 19104.
2 Department of Radiology, Hospital of the University of Pennsylvania, 3400 Spruce St., Philadelphia, PA 19104.
3 Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadephia, PA 19104.



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  		Fig. 1A. —79-year-old man with malignant fibrous histiocytoma. Spot radiograph from pharyngoesophagram obtained with patient in lateral position reveals 4-cm polypoid mass (arrows) arising from posterior pharyngeal wall. Tumor extends from lower oropharynx to upper hypopharynx. Tumor surface is smooth; contour is mildly lobulated. Laryngeal vestibule, laryngeal ventricle, and proximal trachea are coated by barium aspirated because of inability of epiglottis to tilt.

 


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  		Fig. 1B. —79-year-old man with malignant fibrous histiocytoma. Axial image at level of valleculae and epiglottic tip (small arrow) from helical CT shows hypervascular mass (large arrows) arising from right side of posterior pharyngeal wall. Mass is more vascular than adjacent pharyngeal muscles, paraspinal muscles, or tongue. No lymphadenopathy or phleboliths are seen.

 


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  		Fig. 1C. —79-year-old man with malignant fibrous histiocytoma. Low-power photomicrograph shows tumor with pleomorphic features below normal squamous epithelium of posterior pharyngeal wall. (H and E, x100)

 


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  		Fig. 1D. —79-year-old man with malignant fibrous histiocytoma. Higher-power photomicrograph of tumor shows pleomorphic spindle cells with atypical mitoses. (H and E, x400)

 

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