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Palliative Radiofrequency Ablation of a Fungating, Symptomatic Breast Lesion

Eric vanSonnenberg1, Sridhar Shankar2,3, Leroy Parker4, Lawrence Cheung2, Paul R. Morrison2, Stuart G. Silverman2 and Dirk Igelhart5

1 Department of Radiology, Brigham and Women's Hospital, Boston, MA 02115.
2 Department of Radiology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
3 University of Massachusetts Memorial Health Center, Worcester, MA 01655.
4 Department of Medical Oncology, Division of Breast Oncology, Dana-Farber Cancer Insititute, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
5 Department of Surgery, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.



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Fig. 1A. 43-year-old woman with fungating breast lesion. Lesion is at inframammary fold of reconstructed breast, the latter being cephalad to lesion. Lesion is ulcerated and has areas of dried blood.

 


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Fig. 1B. 43-year-old woman with fungating breast lesion. CT-guided radiofrequency ablation of fungating breast tumor with patient under general anesthesia. Noncontrast supine CT scan shows radiofrequency needle probe entering from patient's right in medial portion of tumor.

 


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Fig. 1C. 43-year-old woman with fungating breast lesion. Needle probe is repositioned into lateral and outer portion of tumor for second ablation.

 


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Fig. 1D. 43-year-old woman with fungating breast lesion. MRI pre- and postradiofrequency ablation procedure, showing efficacy of ablation. Preprocedure, T1-weighted spoiled gradient-echo MRI (D) (TR/TE, 7/2.2; TI, 40; flip angle, 10°) after 20 mL of IV gadopentetate dimeglumine are administered and using body coil. Lesion has enhanced notably with contrast medium (arrows). After ablation, T1-weighted spoiled gradient-echo MRI (E) (TR/TE, 7.7/2.028; TI, 40; flip angle, 10°) shows lack of enhancement in lesion. Note deeper breath on MRI compared with CT, as the patient was awake for MRI examination.

 


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Fig. 1E. 43-year-old woman with fungating breast lesion. MRI pre- and postradiofrequency ablation procedure, showing efficacy of ablation. Preprocedure, T1-weighted spoiled gradient-echo MRI (D) (TR/TE, 7/2.2; TI, 40; flip angle, 10°) after 20 mL of IV gadopentetate dimeglumine are administered and using body coil. Lesion has enhanced notably with contrast medium (arrows). After ablation, T1-weighted spoiled gradient-echo MRI (E) (TR/TE, 7.7/2.028; TI, 40; flip angle, 10°) shows lack of enhancement in lesion. Note deeper breath on MRI compared with CT, as the patient was awake for MRI examination.

 


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Fig. 1F. 43-year-old woman with fungating breast lesion. Two weeks postradiofrequency ablation, lesion developed an eschar and was diminished in size.

 

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